Anti-IL1 alpha antibody (ab14306)

Overview

  • Product nameAnti-IL1 alpha antibody
    See all IL1 alpha primary antibodies
  • Description
    Chicken polyclonal to IL1 alpha
  • SpecificityThe antigen was a full length recombinant protein including precursor sequence. The antibody should recognize 1) mature peptide, 2) precursor as a single peptide including preprotein and mature peptide sequence, and 3)precursor sequence that is cleaved from mature peptide.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length protein.

  • Positive control
    • E coli-derived fusion protein.
  • General notesDuring shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 µl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container's cap.

Properties

Applications

Our Abpromise guarantee covers the use of ab14306 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000. Predicted molecular weight: 32 kDa.

Target

  • FunctionProduced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
  • Sequence similaritiesBelongs to the IL-1 family.
  • DomainThe similarity among the IL-1 precursors suggests that the amino ends of these proteins serve some as yet undefined function.
  • Cellular localizationSecreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
  • Information by UniProt
  • Database links
  • Alternative names
    • BAF antibody
    • FAF antibody
    • Hematopoietin 1 antibody
    • Hematopoietin-1 antibody
    • IL 1 alpha antibody
    • IL 1A antibody
    • IL-1 alpha antibody
    • Il-1a antibody
    • IL1 ALPHA antibody
    • IL1 antibody
    • IL1A antibody
    • IL1A_HUMAN antibody
    • IL1F1 antibody
    • Interleukin 1 alpha antibody
    • Interleukin-1 alpha antibody
    • Interleukin1 alpha antibody
    • LAF antibody
    • LEM antibody
    • Preinterleukin 1 alpha antibody
    • Pro interleukin 1 alpha antibody
    see all

Anti-IL1 alpha antibody images

  • Anti-IL1 alpha antibody (ab14306) at 1/2000 dilution + E.coli derived IL1 alpha fusion protein.

    Secondary
    HRP conjugated goat anti IgY at 1/1000 dilution

    Predicted band size : 32 kDa

References for Anti-IL1 alpha antibody (ab14306)

ab14306 has not yet been referenced specifically in any publications.

Product Wall

The molecular weight recognized by ab14306 is high because the protein used in those samples is not endogenous IL1 alpha but and E coli-derived fusion protein as test antigen. Therefore the MW is that of IL1 alpha + that of the "carrier" protein. P...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"