Overview

  • Product name
    Anti-IL1 alpha antibody (Biotin)
    See all IL1 alpha primary antibodies
  • Description
    Goat polyclonal to IL1 alpha (Biotin)
  • Conjugation
    Biotin
  • Tested applications
    Suitable for: ELISA, Sandwich ELISA, WBmore details
  • Species reactivity
    Reacts with: Rat
  • Immunogen

    Highly pure (>98%) recombinant Rat IL1 alpha

  • General notes
    ab84012 is sterile filtered.

Properties

Applications

Our Abpromise guarantee covers the use of ab84012 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
Sandwich ELISA
WB
  • Application notes
    ELISA: Use at a concentration of 0.25 - 1 µg/ml. Allows the detection of at least 0.2 - 0.4 ng/well of recombinant Rat IL1 alpha.
    sELISA: Use at a concentration of 0.25 - 1 µg/ml. Allows the detection of at least 0.2 - 0.4 ng/well of recombinant Rat IL1 alpha.
    WB: Use at a concentration of 0.1 - 0.2 µg/ml. The detection limit for recombinant Rat IL1 alpha is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions. Predicted molecular weight: 31 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
    • Sequence similarities
      Belongs to the IL-1 family.
    • Domain
      The similarity among the IL-1 precursors suggests that the amino ends of these proteins serve some as yet undefined function.
    • Cellular localization
      Secreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
    • Information by UniProt
    • Database links
    • Alternative names
      • BAF antibody
      • FAF antibody
      • Hematopoietin 1 antibody
      • Hematopoietin-1 antibody
      • IL 1 alpha antibody
      • IL 1A antibody
      • IL-1 alpha antibody
      • Il-1a antibody
      • IL1 ALPHA antibody
      • IL1 antibody
      • IL1A antibody
      • IL1A_HUMAN antibody
      • IL1F1 antibody
      • Interleukin 1 alpha antibody
      • Interleukin-1 alpha antibody
      • Interleukin1 alpha antibody
      • LAF antibody
      • LEM antibody
      • Preinterleukin 1 alpha antibody
      • Pro interleukin 1 alpha antibody
      see all

    References

    ab84012 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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