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  • Product nameAnti-IL1 beta antibody [1400.24.17]
    See all IL1 beta primary antibodies
  • Description
    Rat monoclonal [1400.24.17] to IL1 beta
  • SpecificityThis antibody recognizes both the recombinant and the natural form of mouse IL1b.
  • Tested applicationsELISA, Neutralisingmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Mouse IL1 beta



Our Abpromise guarantee covers the use of ab13784 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution. Ab13784 can be used as the capture reagent in a two-site sandwich ELISA for measuring mouse IL1b levels using recombinant mouse IL-1b as the standard. This ELISA measured IL1b in mice with a detection range between 10 pg/ml and 3 ng/ml after zymosan induced inflammation. See Oluyomi AO et al.
Neutralising Use at an assay dependent dilution. See Geiger T et al.


  • FunctionProduced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
  • Sequence similaritiesBelongs to the IL-1 family.
  • DomainThe similarity among the IL-1 precursors suggests that the amino ends of these proteins serve some as yet undefined function.
  • Cellular localizationSecreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
  • Information by UniProt
  • Database links
  • Alternative names
    • Catabolin antibody
    • H1 antibody
    • IL 1 antibody
    • IL 1 beta antibody
    • IL-1 beta antibody
    • IL1 BETA antibody
    • IL1B antibody
    • IL1B_HUMAN antibody
    • IL1F2 antibody
    • Interleukin 1 beta antibody
    • Interleukin-1 beta antibody
    • OAF antibody
    • OTTHUMP00000162031 antibody
    • Preinterleukin 1 beta antibody
    • Pro interleukin 1 beta antibody
    see all

References for Anti-IL1 beta antibody [1400.24.17] (ab13784)

This product has been referenced in:
  • Yang B  et al. Comparison of neurodegeneration and cognitive impairment in neonatal mice exposed to propofol or isoflurane. PLoS One 9:e99171 (2014). WB ; Mouse . Read more (PubMed: 24932894) »
  • Oluyomi AO  et al. Differential effects of prednisolone and indomethacin on zymosan-induced inflammation in a modified murine tissue-chamber model. Inflamm Res 44:350-6 (1995). Read more (PubMed: 8581523) »

See all 3 Publications for this product

Product Wall

Thank you for your inquiry aboutab13784.

I have talked to the lab and they have informed me that the antibody recognizes both the precursor and active form of IL1 Beta.

If there is anything else I can help you with, please let me know.

Thank you for your patience. We produce some of our antibodies in-house and others are sourced from suppliers whose products we believe will be of interest to our customers. This product falls into the latter category. We have just been informed...

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