Anti-IL1 Receptor I antibody (ab19173)

Overview

  • Product nameAnti-IL1 Receptor I antibody
    See all IL1 Receptor I primary antibodies
  • Description
    Mouse monoclonal to IL1 Receptor I
  • SpecificityThis antibody partially inhibits (30-50%) binding of one another to IL1 Receptor. It does not block binding of IL1 to receptor and they do not cross react with receptors for human IL2 or IL4
  • Tested applicationsSuitable for: ELISA, RIA, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    The extracellular domain of the type 1 human IL1 Receptor.

  • EpitopeSpecific epitopes are unknown.

Properties

Applications

Our Abpromise guarantee covers the use of ab19173 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
RIA
ICC/IF
  • Application notesELISA: Can be used as capture reagents or second antibody at a concentration of 5 µg/ml.
    ICC/IF: IL1 Receptor can be detected on acetone fixed cultured cells using antibody concentrations of 10-100 ug/ml
    RIA: 20-30 ng/ml of this antibody will bind radiolabelled IL1 Receptor.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionReceptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappa-B. Signaling involves formation of a ternary complex containing IL1RAP, TOLLIP, MYD88, and IRAK1 or IRAK2.
    • Sequence similaritiesBelongs to the interleukin-1 receptor family.
      Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
      Contains 1 TIR domain.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Antigen CD121a antibody
      • CD121 antigen-like family member A antibody
      • CD121a antibody
      • CD121a antigen antibody
      • D2S1473 antibody
      • IL 1 antibody
      • IL 1R 1 antibody
      • IL 1R alpha antibody
      • IL 1RT1 antibody
      • IL-1R-1 antibody
      • IL-1R-alpha antibody
      • IL-1RT-1 antibody
      • IL-1RT1 antibody
      • IL1 inhibitor antibody
      • IL1R antibody
      • IL1R1 antibody
      • IL1R1_HUMAN antibody
      • IL1RA antibody
      • IL1RN antibody
      • IL1RT1 antibody
      • Interleukin 1 receptor alpha type 1 antibody
      • Interleukin 1 receptor antagonist protein (IRAP) antibody
      • Interleukin 1 receptor type I antibody
      • Interleukin receptor 1 antibody
      • Interleukin-1 receptor alpha antibody
      • Interleukin-1 receptor type 1 antibody
      • Interleukin-1 receptor type I antibody
      • p80 antibody
      see all

    References for Anti-IL1 Receptor I antibody (ab19173)

    ab19173 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your enquiry. The concentration of this antibody is 1.1mg/ml. Therefore the antibody has a volume of 181ul (200ug). I hope this information helps, please do not hesitate to contact us if you need any more advice or information.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"