Overview

  • Product nameAnti-IL1 Receptor I antibody [BDI204]
    See all IL1 Receptor I primary antibodies
  • Description
    Mouse monoclonal [BDI204] to IL1 Receptor I
  • SpecificityReacts with cell surface and soluble human IL-1 receptor. Does not block binding of IL-1 to receptor. Does not cross react with receptors for IL-2 or IL-4.
  • Tested applicationsSuitable for: ICC/IF, ELISA, RIAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    The extracellular domain of the type I human IL-1 receptor.

Properties

Applications

Our Abpromise guarantee covers the use of ab20876 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF
ELISA
RIA
  • Application notesELISA: Use at a concentration of 5 µg/ml.
    ICC/IF: Use at an assay dependent dilution (see PMID: 17210691).
    RIA: Use at a concentration of 0.02 - 0.03 µg/ml.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionReceptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappa-B. Signaling involves formation of a ternary complex containing IL1RAP, TOLLIP, MYD88, and IRAK1 or IRAK2.
    • Sequence similaritiesBelongs to the interleukin-1 receptor family.
      Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
      Contains 1 TIR domain.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Antigen CD121a antibody
      • CD121 antigen-like family member A antibody
      • CD121a antibody
      • CD121a antigen antibody
      • D2S1473 antibody
      • IL 1 antibody
      • IL 1R 1 antibody
      • IL 1R alpha antibody
      • IL 1RT1 antibody
      • IL-1R-1 antibody
      • IL-1R-alpha antibody
      • IL-1RT-1 antibody
      • IL-1RT1 antibody
      • IL1 inhibitor antibody
      • IL1R antibody
      • IL1R1 antibody
      • IL1R1_HUMAN antibody
      • IL1RA antibody
      • IL1RN antibody
      • IL1RT1 antibody
      • Interleukin 1 receptor alpha type 1 antibody
      • Interleukin 1 receptor antagonist protein (IRAP) antibody
      • Interleukin 1 receptor type I antibody
      • Interleukin receptor 1 antibody
      • Interleukin-1 receptor alpha antibody
      • Interleukin-1 receptor type 1 antibody
      • Interleukin-1 receptor type I antibody
      • p80 antibody
      see all

    References for Anti-IL1 Receptor I antibody [BDI204] (ab20876)

    This product has been referenced in:
    • Gray-Schopfer VC  et al. Tumor necrosis factor-alpha blocks apoptosis in melanoma cells when BRAF signaling is inhibited. Cancer Res 67:122-9 (2007). Read more (PubMed: 17210691) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"