Overview

  • Product nameAnti-IL10 antibody [B-S10]
    See all IL10 primary antibodies
  • Description
    Mouse monoclonal [B-S10] to IL10
  • SpecificityThis antibody recognises both natural and recombinant IL10. No cross reactivity is observed with IL1, IL2, IL6, IL8 and TNF alpha.
  • Tested applicationsSuitable for: ELISA, Neutralisingmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein (Human).

Properties

Applications

Our Abpromise guarantee covers the use of ab22771 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
Neutralising
  • Application notesELISA: Use at an assay dependent dilution.
    Neut: Use at an assay dependent dilution. 600pg of ab22771 neutralised 50% of the activity of 1pg of IL10. Removal of sodium azide is recommended prior to functional assays.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionInhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.
    • Tissue specificityProduced by a variety of cell lines, including T-cells, macrophages, mast cells and other cell types.
    • Sequence similaritiesBelongs to the IL-10 family.
    • Cellular localizationSecreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • CSIF antibody
      • Cytokine synthesis inhibitory factor antibody
      • GVHDS antibody
      • IL 10 antibody
      • IL-10 antibody
      • IL10 antibody
      • IL10_HUMAN antibody
      • IL10A antibody
      • Interleukin 10 antibody
      • Interleukin-10 antibody
      • MGC126450 antibody
      • MGC126451 antibody
      • T-cell growth inhibitory factor antibody
      • TGIF antibody
      see all

    References for Anti-IL10 antibody [B-S10] (ab22771)

    This product has been referenced in:
    • Tsuji H  et al. Xenografted human amniotic membrane-derived mesenchymal stem cells are immunologically tolerated and transdifferentiated into cardiomyocytes. Circ Res 106:1613-23 (2010). Read more (PubMed: 20508201) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"