Overview

  • Product nameAnti-IL10RA antibody [37607.11]
    See all IL10RA primary antibodies
  • Description
    Mouse monoclonal [37607.11] to IL10RA
  • SpecificityWe have feedback that the antibody has a low sensitivity in a western blot application. The antibody could work, however for detection of endogenous levels of IL-10Ra, it will be necessary to use more antibody than 1-2ug/ml
  • Tested applicationsSuitable for: Neutralisingmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein (Human).

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: PBS
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • Clone number37607.11
  • IsotypeIgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab10777 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Neutralising Use at an assay dependent concentration.

Target

  • FunctionReceptor for IL10; binds IL10 with a high affinity.
  • Tissue specificitySpleen, thymus, and PBMC. Weak expression in pancreas, skeletal muscle, brain, heart, and kidney. Placenta, lung, and liver showed intermediate levels. Monocytes, B-cells, large granular lymphocytes, and T-cells express high levels.
  • Involvement in diseaseInflammatory bowel disease 28
  • Sequence similaritiesBelongs to the type II cytokine receptor family.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD210 antibody
    • CDw210a antibody
    • CDw210a antigen antibody
    • HIL 10R antibody
    • HIL10R antibody
    • I10R1_HUMAN antibody
    • IL 10R 1 antibody
    • IL 10R A antibody
    • IL 10R antibody
    • IL 10R1 antibody
    • IL-10 receptor subunit alpha antibody
    • IL-10R subunit 1 antibody
    • IL-10R subunit alpha antibody
    • IL-10R1 antibody
    • IL-10RA antibody
    • IL10R antibody
    • IL10R1 antibody
    • IL10RA antibody
    • Interleukin 10 receptor alpha antibody
    • Interleukin 10 receptor alpha chain antibody
    • Interleukin-10 receptor subunit 1 antibody
    • Interleukin-10 receptor subunit alpha antibody
    see all

References for Anti-IL10RA antibody [37607.11] (ab10777)

This product has been referenced in:
  • Victoria S  et al. Activation of Toll-like receptor 2 increases macrophage resistance to HIV-1 infection. Immunobiology 218:1529-36 (2013). Read more (PubMed: 23891328) »
  • Drukker M  et al. Isolation of primitive endoderm, mesoderm, vascular endothelial and trophoblast progenitors from human pluripotent stem cells. Nat Biotechnol 30:531-42 (2012). Human . Read more (PubMed: 22634564) »

See all 2 Publications for this product

Product Wall



The concentrations noted on our online datasheets for these products are the only concentrations available at this time. However, one easy way to increase the concentration for these products would be to use a 10KdA moleuclar weight cut off s...

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Thank you for your enquiry. The concentrations used for each of these applications are listed in the application notes section of each datasheet. I have included links back to the datasheets for the two antibodies at the end of this email for your ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"