Overview

  • Product name
  • Description
    Rabbit polyclonal to IL10RA
  • Specificity
    ab61775 detects endogenous levels of total IL10RA protein.
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic non-phosphopeptide derived from human IL10RA around the phosphorylation site of tyrosine 496 (K-G-Y-L-K).

  • Positive control
    • HepG2 cell extracts treated with Na2VO3 (0.3nM, 40mins).

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab61775 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/10000.
WB 1/500 - 1/1000. Detects a band of approximately 63 kDa (predicted molecular weight: 63 kDa).

Target

  • Function
    Receptor for IL10; binds IL10 with a high affinity.
  • Tissue specificity
    Spleen, thymus, and PBMC. Weak expression in pancreas, skeletal muscle, brain, heart, and kidney. Placenta, lung, and liver showed intermediate levels. Monocytes, B-cells, large granular lymphocytes, and T-cells express high levels.
  • Involvement in disease
    Inflammatory bowel disease 28
  • Sequence similarities
    Belongs to the type II cytokine receptor family.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD210 antibody
    • CDw210a antibody
    • CDw210a antigen antibody
    • HIL 10R antibody
    • HIL10R antibody
    • I10R1_HUMAN antibody
    • IL 10R 1 antibody
    • IL 10R A antibody
    • IL 10R antibody
    • IL 10R1 antibody
    • IL-10 receptor subunit alpha antibody
    • IL-10R subunit 1 antibody
    • IL-10R subunit alpha antibody
    • IL-10R1 antibody
    • IL-10RA antibody
    • IL10R antibody
    • IL10R1 antibody
    • IL10RA antibody
    • Interleukin 10 receptor alpha antibody
    • Interleukin 10 receptor alpha chain antibody
    • Interleukin-10 receptor subunit 1 antibody
    • Interleukin-10 receptor subunit alpha antibody
    see all

Images

  • All lanes : Anti-IL10RA antibody (ab61775) at 1/500 dilution

    Lane 1 : HepG2 cell extracts treated with Na2VO3 (0.3nM, 40mins)
    Lane 2 : HepG2 cell extracts treated with Na2VO3 (0.3nM, 40mins) with immunising peptide


    Predicted band size : 63 kDa
    Observed band size : 63 kDa

References

This product has been referenced in:
  • García-Prieto E  et al. Resistance to bleomycin-induced lung fibrosis in MMP-8 deficient mice is mediated by interleukin-10. PLoS One 5:e13242 (2010). WB ; Mouse . Read more (PubMed: 20949050) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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