Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionReceptor for IL10; binds IL10 with a high affinity.
Tissue specificitySpleen, thymus, and PBMC. Weak expression in pancreas, skeletal muscle, brain, heart, and kidney. Placenta, lung, and liver showed intermediate levels. Monocytes, B-cells, large granular lymphocytes, and T-cells express high levels.
Involvement in diseaseInflammatory bowel disease 28
Sequence similaritiesBelongs to the type II cytokine receptor family.
Anti-IL10RA antibody (ab93470) at 1/100 dilution + MCF7 cell lysate at 35 µg
Predicted band size : 63 kDa
References for Anti-IL10RA antibody (ab93470)
This product has been referenced in:
Shi J et al. Anti-fibrotic actions of interleukin-10 against hypertrophic scarring by activation of PI3K/AKT and STAT3 signaling pathways in scar-forming fibroblasts. PLoS One9:e98228 (2014).
Read more (PubMed: 24878845) »