Overview

  • Product nameAnti-IL11RA antibody
    See all IL11RA primary antibodies
  • Description
    Rabbit polyclonal to IL11RA
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant fragment, corresponding to amino acids 177-370 of Human IL11RA (BC003110).

  • Positive control
    • Human fetal liver, heart, colon lysates, Human prostate carcinoma

Properties

Applications

Our Abpromise guarantee covers the use of ab109697 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/2000. Predicted molecular weight: 45 kDa.
IHC-P 1/100 - 1/500.

Target

  • FunctionReceptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells.
  • Tissue specificityExpressed in a number of cell lines, including the myelogenous leukemia cell line K562, the megakaryocytic leukemia cell line Mo7E, the erythroleukemia cell line TF1, and the osteosarcoma cell lines, MG-63 and Saos-2. Also expressed in normal and malignant prostate epithelial cell lines. Expression levels are increased in prostate carcinoma.
  • Sequence similaritiesBelongs to the type I cytokine receptor family. Type 3 subfamily.
    Contains 2 fibronectin type-III domains.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CRSDA antibody
    • hCG_2011440 antibody
    • I11RA_HUMAN antibody
    • IL-11 receptor subunit alpha antibody
    • IL-11R subunit alpha antibody
    • IL-11R-alpha antibody
    • IL-11RA antibody
    • IL11RA antibody
    • Interleukin 11 receptor alpha antibody
    • Interleukin 11 receptor alpha chain antibody
    • Interleukin-11 receptor subunit alpha antibody
    • MGC2146 antibody
    see all

Anti-IL11RA antibody images

  • All lanes : Anti-IL11RA antibody (ab109697) at 1/1000 dilution

    Lane 1 : Human fetal liver lysate
    Lane 2 : Human fetal heart lysate
    Lane 3 : Human fetal colon lysate


    Predicted band size : 45 kDa
  • ab109697 at 1/100 dilution staining IL11RA in Human prostate carcinoma by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.

References for Anti-IL11RA antibody (ab109697)

ab109697 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"