Use at an assay dependent concentration. Neutralizes the bioactivity of natural or recombinant IL12 both in vivo and in vitro.
1/200 - 1/400. ab18407-Rat monoclonal IgG1, is suitable for use as an isotype control with this antibody.
FunctionCytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC.
Sequence similaritiesBelongs to the IL-6 superfamily.