The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Intra-cytoplasmic Flow Cyt: 1/10.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
IL12 is a heterodimeric cytokine comprised of p35 and p40 subunits. IL12 plays a central role in mediating cell mediated immunity, promoting differentiation of CD4+ T cells to the Th1 subset and of CD8+ T cells into mature cytotoxic T lymphocytes (CTLs). IL12 is a potent stimulator of NK cells. IL12 therapy has been suggested as a method of enhancing cytocidal anti tumour immune responses.