Anti-IL12 p40 + IL12 p70 antibody [B-P24] (ab27364)

Overview

  • Product name
    Anti-IL12 p40 + IL12 p70 antibody [B-P24]
    See all IL12 p40 + IL12 p70 primary antibodies
  • Description
    Mouse monoclonal [B-P24] to IL12 p40 + IL12 p70
  • Specificity
    ab27364 recognizes both natural and recombinant human IL12 p40 + p70. Blocks IL12 induced proliferation on PHA and IL2 activated lymphocytes.
  • Tested applications
    Suitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant IL12 (Human)

Properties

Applications

Our Abpromise guarantee covers the use of ab27364 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
  • Application notes
    Intra-cytoplasmic Flow Cyt: 1/10.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Relevance
      IL12 is a heterodimeric cytokine comprised of p35 and p40 subunits. IL12 plays a central role in mediating cell mediated immunity, promoting differentiation of CD4+ T cells to the Th1 subset and of CD8+ T cells into mature cytotoxic T lymphocytes (CTLs). IL12 is a potent stimulator of NK cells. IL12 therapy has been suggested as a method of enhancing cytocidal anti tumour immune responses.
    • Cellular localization
      Secreted
    • Database links
    • Alternative names
      • CLMF p35 antibody
      • CLMF p40 antibody
      • CLMF1 antibody
      • CLMF2 antibody
      • IL12 subunit p35 antibody
      • IL12 subunit p40 antibody
      • IL12A antibody
      • IL12B antibody
      • NKSF antibody
      • NKSF2 antibody
      see all

    References

    ab27364 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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