Anti-IL13 antibody [A130D 12G5 1E4] (ab52538)

Overview

  • Product name
    Anti-IL13 antibody [A130D 12G5 1E4]
    See all IL13 primary antibodies
  • Description
    Mouse monoclonal [A130D 12G5 1E4] to IL13
  • Host species
    Mouse
  • Specificity
    Recognizes recombinant and native rat IL 13
  • Tested applications
    Suitable for: WB, ELISA, Flow Cyt, Dot blotmore details
  • Species reactivity
    Reacts with: Rat
  • Immunogen

    Recombinant full length protein (Rat)

  • Positive control
    • FACS: intracellular IL 13 can be detected in PMA/ionophore-stimulated rat splenocytes

Properties

Applications

Our Abpromise guarantee covers the use of ab52538 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 14 kDa.
ELISA Use at an assay dependent concentration.
Flow Cyt Use 0.1-1µg for 106 cells.

ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

 

Dot blot 1/500 - 1/1000.

Target

  • Function
    Cytokine (PubMed:8096327, PubMed:8097324). Inhibits inflammatory cytokine production (PubMed:8096327). Synergizes with IL2 in regulating interferon-gamma synthesis (PubMed:8096327). May be critical in regulating inflammatory and immune responses (PubMed:8096327, PubMed:8097324). Positively regulates IL31RA expression in macrophages.
  • Involvement in disease
    Allergic rhinitis
  • Sequence similarities
    Belongs to the IL-4/IL-13 family.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Allergic rhinitis antibody
    • ALRH antibody
    • BHR1 antibody
    • Bronchial hyperresponsiveness 1 (bronchial asthma) antibody
    • IL 13 antibody
    • IL-13 antibody
    • Il13 antibody
    • IL13_HUMAN antibody
    • Interleukin 13 antibody
    • Interleukin-13 antibody
    • MGC116786 antibody
    • MGC116788 antibody
    • MGC116789 antibody
    • NC30 antibody
    • P600 antibody
    see all

References

ab52538 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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