Overview

  • Product name
  • Description
    Rabbit polyclonal to IL15
  • Tested applications
    Suitable for: WB, ELISA, Neutralising, Sandwich ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Highly pure (>98%) recombinant hIL-15 (human Interleukin-15)

  • General notes


    Interleukin-15 is a potent lymphoid cell growth factor, which exerts it's biological activities primarily on T cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab9581 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.2 µg/ml.
ELISA Use a concentration of 0.5 µg/ml. Allows the detection of 0.2 - 0.4 ng/well of recombinant hIL-15 (assuming 100 µl/well antibody solution).
Neutralising Use a concentration of 0.15 - 0.2 µg/ml. for one-half maximal inhibition [ND50] of the biological activity of hIL-15 (1.0 ng/ml).
Sandwich ELISA Use at an assay dependent dilution. Use as Detection antibody. Allows the detection of 0.2 - 0.4 ng/well of recombinant hIL-15 (assuming 100 µl/well antibody solution).

Target

  • Function
    Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL-15 requires interaction of IL-15 with components of IL-2R, including IL-2R beta and probably IL-2R gamma but not IL-2R alpha.
  • Tissue specificity
    Most abundant in placenta and skeletal muscle. It is also detected in the heart, lung, liver and kidney. IL15-S21AA is preferentially expressed in tissues such as testis and thymus.
  • Sequence similarities
    Belongs to the IL-15/IL-21 family.
  • Cellular localization
    Secreted and Cytoplasm. Nucleus. IL15-S21AA is not secreted, but rather is stored intracellularly, appearing in the nucleus and cytoplasmic components.
  • Information by UniProt
  • Database links
  • Alternative names
    • IL 15 antibody
    • IL-15 antibody
    • IL15 antibody
    • IL15_HUMAN antibody
    • Interleukin 15 antibody
    • Interleukin-15 antibody
    • Interleukin15 antibody
    • MGC9721 antibody
    see all

References for Anti-IL15 antibody (ab9581)

ab9581 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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