• FormLyophilised:Reconstitute with 200µl of sterile water. Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary.
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage bufferPBS, pH 7.4, no preservative, sterile filtered
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • Isotypeunknown
  • Light chain typeunknown
  • Research areas

Associated products


Our Abpromise guarantee covers the use of ab9565 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.2 µg/ml.
ELISA Use a concentration of 0.5 µg/ml. Allows the detection of 0.2 - 0.4 ng/well of recombinant hIL-17 (assuming 100 µl/well antibody solution).
Neutralising Use a concentration of 0.1 - 0.18 µg/ml. for one-half maximal inhibition [ND50] of the biological activity of hIL-17 (6.0 ng/ml).
IHC-P Use at an assay dependent concentration.


  • FunctionLigand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines (PubMed:8676080).
  • Tissue specificityRestricted to activated memory T-cells.
  • Sequence similaritiesBelongs to the IL-17 family.
  • Post-translational
    Found both in glycosylated and nonglycosylated forms.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • CTLA 8 antibody
    • CTLA-8 antibody
    • CTLA8 antibody
    • Cytotoxic T lymphocyte associated antigen 8 antibody
    • Cytotoxic T lymphocyte associated protein 8 antibody
    • Cytotoxic T lymphocyte associated serine esterase 8 antibody
    • Cytotoxic T-lymphocyte-associated antigen 8 antibody
    • IL 17A antibody
    • IL-17 antibody
    • IL-17A antibody
    • IL17 antibody
    • IL17_HUMAN antibody
    • Il17a antibody
    • Interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8) antibody
    • Interleukin 17A antibody
    • Interleukin-17A antibody
    • Interleukin17 antibody
    • Interleukin17A antibody
    • OTTHUMP00000016597 antibody
    • OTTMUSP00000046003 antibody
    see all

References for Anti-IL17 antibody (ab9565)

This product has been referenced in:
  • Harvey BS  et al. Interleukin 17A evoked mucosal damage is attenuated by cannabidiol and anandamide in a human colonic explant model. Cytokine 65:236-44 (2014). WB, IHC-P ; Human . Read more (PubMed: 24238999) »
  • Rodrigues-Díez R  et al. IL-17A is a novel player in dialysis-induced peritoneal damage. Kidney Int N/A:N/A (2014). Read more (PubMed: 24552849) »

See all 4 Publications for this product

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Blocking step Goat Serum as blocking agent for 30 minute(s) · Concentration: 50% · Temperature: 23°C
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: Citrate buffer (pH 6.0)
Sample Human Tissue sections (Colonic Mucosa)
Specification Colonic Mucosa
Permeabilization Yes - 0.1% Triton X-100
Fixative Formaldehyde

Abcam user community

Verified customer

Submitted Jul 02 2013

Thank you for your enquiry regarding ab9565.

We do not have any recommendations for lysis buffers, as we do not test this antibody on cell lysate in our labs. As the datasheet indicates, this antibody has been tested on recombinant hIL-17 at ...

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