Overview

Properties

  • FormLyophilised:Reconstitute in sterile PBS containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml.
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: None
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein A purified
  • Purification notesab84240 was purified by affinity chromatography and then biotinylated and filter sterilised.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab84240 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
Sandwich ELISA
WB
  • Application notesELISA: Use at a concentration of 0.25 - 1 µg/ml. Allows the detection of at least 0.2 - 0.4 ng/well of recombinant Human IL17B.
    sELISA: Use at a concentration of 0.25 - 1 µg/ml. Allows the detection of at least 0.2 - 0.4 ng/well of recombinant Human IL17B.
    WB: Use at a concentration of 0.1 - 0.2 µg/ml. The detection limit for recombinant Human IL17B is 1.5 - 3.0 ng/lane under either reducing or non-reducing conditions. Predicted molecular weight: 20 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionLigand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines (PubMed:8676080).
    • Tissue specificityRestricted to activated memory T-cells.
    • Sequence similaritiesBelongs to the IL-17 family.
    • Post-translational
      modifications
      Found both in glycosylated and nonglycosylated forms.
    • Cellular localizationSecreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • CTLA 8 antibody
      • CTLA-8 antibody
      • CTLA8 antibody
      • Cytotoxic T lymphocyte associated antigen 8 antibody
      • Cytotoxic T lymphocyte associated protein 8 antibody
      • Cytotoxic T lymphocyte associated serine esterase 8 antibody
      • Cytotoxic T-lymphocyte-associated antigen 8 antibody
      • IL 17A antibody
      • IL-17 antibody
      • IL-17A antibody
      • IL17 antibody
      • IL17_HUMAN antibody
      • Il17a antibody
      • Interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8) antibody
      • Interleukin 17A antibody
      • Interleukin-17A antibody
      • Interleukin17 antibody
      • Interleukin17A antibody
      • OTTHUMP00000016597 antibody
      • OTTMUSP00000046003 antibody
      see all

    References for Anti-IL17 antibody (Biotin) (ab84240)

    ab84240 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab84240.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"