Anti-IL17 antibody [TC11-18H10] (ab118869)


  • Product nameAnti-IL17 antibody [TC11-18H10]
    See all IL17 primary antibodies
  • Description
    Rat monoclonal [TC11-18H10] to IL17
  • Tested applicationsSuitable for: Sandwich ELISA, WB, IHC-P, Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    recombinant mouse IL-17A.

  • Positive control
    • Mouse spleen tissue


Associated products


Our Abpromise guarantee covers the use of ab118869 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Sandwich ELISA Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 17 kDa.
IHC-P Use a concentration of 10 µg/ml.
Flow Cyt Use at an assay dependent concentration. ab18407-Rat monoclonal IgG1, is suitable for use as an isotype control with this antibody.


  • FunctionLigand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines (PubMed:8676080).
  • Tissue specificityRestricted to activated memory T-cells.
  • Sequence similaritiesBelongs to the IL-17 family.
  • Post-translational
    Found both in glycosylated and nonglycosylated forms.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • CTLA 8 antibody
    • CTLA-8 antibody
    • CTLA8 antibody
    • Cytotoxic T lymphocyte associated antigen 8 antibody
    • Cytotoxic T lymphocyte associated protein 8 antibody
    • Cytotoxic T lymphocyte associated serine esterase 8 antibody
    • Cytotoxic T-lymphocyte-associated antigen 8 antibody
    • IL 17A antibody
    • IL-17 antibody
    • IL-17A antibody
    • IL17 antibody
    • IL17_HUMAN antibody
    • Il17a antibody
    • Interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8) antibody
    • Interleukin 17A antibody
    • Interleukin-17A antibody
    • Interleukin17 antibody
    • Interleukin17A antibody
    • OTTHUMP00000016597 antibody
    • OTTMUSP00000046003 antibody
    see all

Anti-IL17 antibody [TC11-18H10] images

  • Paraffin-embedded Mouse spleen tissue labelled with ab118869 at 10 µg/ml

References for Anti-IL17 antibody [TC11-18H10] (ab118869)

ab118869 has not yet been referenced specifically in any publications.

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Immunohistochemistry (Frozen sections)
Sample Mouse Tissue sections (Tumour)
Permeabilization Yes - PBS 0.3% Triton
Specification Tumour
Blocking step Serum as blocking agent for 30 minute(s) · Concentration: 5% · Temperature: 21°C
Fixative 3:1 Actone:Ethanol

Benjamin Kirkup

Verified customer

Submitted Aug 16 2016

Thank you for your message and for kindly providing these details.

I look forward to hearing from you with the results of the next experiment. I hope these will be successful. Please do not hesitate to let me know if the suggestions do not w...

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Thank you for taking the time to contact us with these details. I am sorry to hear you have had difficulty obtaining satisfactory results from this antibody.

The details you have kindly provided will enable us to investigate this case for yo...

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Thank you for your enquiry.

I would like to reassure you that our antibodies have all been tested successfully and would be covered by our guarantee in the applications and species listed on the datasheets. Therefore, any IL17 antibody teste...

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Gracias por tu respuesta.

Acabo de realizar el nuevo pedido de ab91649 completamente gratuito. El número de pedido es XXXXX, recibirás próximamente una confirmación automática del mismo.

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Gracias por enviarnos el cuestionario completo. Aparte de resultarnos útiles a nosotros para entender mejor el problema por el cual no se ha obtenido la tinción deseada, nos aporta información para monitorizar la calidad de nuestro...

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Tal y como hemos quedado por teléfono te envío el cuestionario para Immunohistoquímica, no lleva mucho tiempo rellenarlo, y nos ayuda a monitorizar las quejas recibidas de nuestros productos y a entender mejor el problema. Si puede...

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