The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent dilution.
FunctionLigand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines (PubMed:8676080).
Tissue specificityRestricted to activated memory T-cells.
Sequence similaritiesBelongs to the IL-17 family.
Post-translational modificationsFound both in glycosylated and nonglycosylated forms.
Interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8) antibody
Interleukin 17A antibody
References for Anti-IL17 antibody [TC11-18H10] (ab47794)
This product has been referenced in:
Schubert D et al. Immunization with glucose-6-phosphate isomerase induces T cell-dependent peripheral polyarthritis in genetically unaltered mice. J Immunol172:4503-9 (2004).
Read more (PubMed: 15034067) »