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Rat monoclonal [RM0104-10B27] to IL17A Receptor
This antibody detects mouse IL17A Receptor in Western blotting, but not IL17B Receptor.
Mouse recombinant protein of the extracellular domain of IL17A Receptor
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Concentration information loading...
Protein A purified
The IgG fraction of culture supernatant was purified by Protein A affinity chromatography.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Predicted molecular weight: 96 kDa.
Receptor for IL17A and IL17F. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling.
Involvement in disease
Defects in IL17RA are the cause of familial candidiasis type 5 (CANDF5) [MIM:613953]. CANDF5 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans.
Contains 1 SEFIR domain.
Information by UniProt
CD217 antigen antibody
References for Anti-IL17A Receptor antibody [RM0104-10B27] (ab86487)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"