Overview

  • Product name
    Anti-IL17A Receptor antibody [RM0104-10B27]
    See all IL17A Receptor primary antibodies
  • Description
    Rat monoclonal [RM0104-10B27] to IL17A Receptor
  • Specificity
    This antibody detects mouse IL17A Receptor in Western blotting, but not IL17B Receptor.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Mouse recombinant protein of the extracellular domain of IL17A Receptor

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Protein A purified
  • Purification notes
    The IgG fraction of culture supernatant was purified by Protein A affinity chromatography.
  • Clonality
    Monoclonal
  • Clone number
    RM0104-10B27
  • Isotype
    IgG2
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab86487 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 96 kDa.

Target

  • Function
    Receptor for IL17A and IL17F. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling.
  • Tissue specificity
    Widely expressed.
  • Involvement in disease
    Defects in IL17RA are the cause of familial candidiasis type 5 (CANDF5) [MIM:613953]. CANDF5 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans.
  • Sequence similarities
    Contains 1 SEFIR domain.
  • Post-translational
    modifications
    Glycosylated.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CANDF5 antibody
    • CD217 antibody
    • CD217 antigen antibody
    • CDw217 antibody
    • CTLA8 antibody
    • HIL 17R antibody
    • hIL17R antibody
    • I17RA_HUMAN antibody
    • IL 17 receptor A antibody
    • IL 17 receptor antibody
    • IL 17RA antibody
    • IL-17 receptor A antibody
    • IL-17RA antibody
    • IL17 antibody
    • IL17A receptor antibody
    • IL17R antibody
    • IL17RA antibody
    • IMD51 antibody
    • Interleukin 17 receptor A antibody
    • Interleukin-17 receptor A antibody
    • MGC10262 antibody
    see all

References

This product has been referenced in:
  • Deguise MO  et al. Differential induction of muscle atrophy pathways in two mouse models of spinal muscular atrophy. Sci Rep 6:28846 (2016). WB . Read more (PubMed: 27349908) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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