Anti-IL17B Receptor antibody (ab77524)

Overview

  • Product nameAnti-IL17B Receptor antibody
    See all IL17B Receptor primary antibodies
  • Description
    Rabbit polyclonal to IL17B Receptor
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Cow
  • Immunogen

    Synthetic peptide conjugated to KLH derived from within residues 100 - 200 of Human IL17B Receptor.

    (Peptide available as ab95416.)

  • Positive control
    • This antibody gave a positive signal in Human liver tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab77524 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 49 kDa (predicted molecular weight: 55 kDa).

Target

  • RelevanceRecently, a number of cytokines belonging to the interleukin IL17 family have been identified. These are termed as IL17B, IL17C and IL17E. IL17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis, multiple sclerosis, and promotion of tumor growth. IL17B, C, and E like IL17 are able to induce proinflammatory responses. However, they do not bind to the IL17 receptor suggesting that additional IL17R related receptor might exist. Receptor for IL17B and IL17E have been independently isolated and have been designated as EV127 (in mouse) and IL17RH1 (in human), respectively. IL17E induces activation of NFkB pathway and like IL17 also induces production of IL8. IL17RH1 mRNA is highly expressed in Kidney and liver and at moderate level in small intestine, colon, and brain.
  • Cellular localizationType I membrane protein (isoform 1). Secreted (isoform 2).
  • Database links
  • Alternative names
    • CRL 4 antibody
    • CRL4 antibody
    • Cytokine receptor CRL4 antibody
    • EVI 27 antibody
    • EVI27 antibody
    • IL 17 receptor B antibody
    • IL 17 receptor homolog 1 antibody
    • IL 17B receptor antibody
    • IL 17RB antibody
    • IL 17Rh1 antibody
    • IL17BR antibody
    • IL17RB antibody
    • IL17RH1 antibody
    • Interleukin 17 receptor B antibody
    • Interleukin 17 receptor homolog 1 antibody
    • Interleukin 17 receptor homolog antibody
    • Interleukin 17B receptor antibody
    • MGC5245 antibody
    see all

Anti-IL17B Receptor antibody images

  • Anti-IL17B Receptor antibody (ab77524) at 1 µg/ml + Human liver tissue lysate - total protein (ab29889) at 10 µg

    Secondary
    Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 55 kDa
    Observed band size : 49 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 46 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 20 minutes

References for Anti-IL17B Receptor antibody (ab77524)

ab77524 has not yet been referenced specifically in any publications.

Product Wall

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I am sorry to hear that the antibody failed again. We unfortunately have same lot in stock; would you like try a new vial?
Alternatively I can also offer you a different antibody however because ab77524 is produced by our own lab so if this fails ...

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Thank you for contacting us. I am very sorry to hear that you are experiencing difficulties with the current vial you received.
As discussed please try the antibody at 5 or 10 ug/ml; if it fails please drop me an email, I will be happy to offer yo...

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