Anti-IL17B Receptor antibody [RM0105-9J28] (ab86488)

Overview

  • Product nameAnti-IL17B Receptor antibody [RM0105-9J28]
    See all IL17B Receptor primary antibodies
  • Description
    Rat monoclonal [RM0105-9J28] to IL17B Receptor
  • SpecificityThis antibody detects mouse IL17B Receptor in Western blotting, but not mouse IL17A receptor
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Mouse recombinant protein of the extracellular domain of IL17B Receptor

Properties

Applications

Our Abpromise guarantee covers the use of ab86488 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 56 kDa.

Target

  • RelevanceRecently, a number of cytokines belonging to the interleukin IL17 family have been identified. These are termed as IL17B, IL17C and IL17E. IL17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis, multiple sclerosis, and promotion of tumor growth. IL17B, C, and E like IL17 are able to induce proinflammatory responses. However, they do not bind to the IL17 receptor suggesting that additional IL17R related receptor might exist. Receptor for IL17B and IL17E have been independently isolated and have been designated as EV127 (in mouse) and IL17RH1 (in human), respectively. IL17E induces activation of NFkB pathway and like IL17 also induces production of IL8. IL17RH1 mRNA is highly expressed in Kidney and liver and at moderate level in small intestine, colon, and brain.
  • Cellular localizationType I membrane protein (isoform 1). Secreted (isoform 2).
  • Database links
  • Alternative names
    • CRL 4 antibody
    • CRL4 antibody
    • Cytokine receptor CRL4 antibody
    • EVI 27 antibody
    • EVI27 antibody
    • IL 17 receptor B antibody
    • IL 17 receptor homolog 1 antibody
    • IL 17B receptor antibody
    • IL 17RB antibody
    • IL 17Rh1 antibody
    • IL17BR antibody
    • IL17RB antibody
    • IL17RH1 antibody
    • Interleukin 17 receptor B antibody
    • Interleukin 17 receptor homolog 1 antibody
    • Interleukin 17 receptor homolog antibody
    • Interleukin 17B receptor antibody
    • MGC5245 antibody
    see all

References for Anti-IL17B Receptor antibody [RM0105-9J28] (ab86488)

ab86488 has not yet been referenced specifically in any publications.

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The subisotype ofab86488 is IgG2a. Thus, the recommended isotype control to be used in flow cytometry would be ab18450.

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Flow cytometry has not yet been tested with this antibody. Therefore, we do not have data to show if and how well it would work in this application. But for UNTESTED species and/or applications, we have establish...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"