Overview

  • Product name
    Anti-IL17F antibody (Biotin)
    See all IL17F primary antibodies
  • Description
    Rabbit polyclonal to IL17F (Biotin)
  • Conjugation
    Biotin
  • Tested applications
    Suitable for: WB, Sandwich ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Highly pure (>98%) recombinant hIL-17F (human IL-17F).

Properties

Applications

Our Abpromise guarantee covers the use of ab46001 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 18 kDa.
Sandwich ELISA Use a concentration of 0.25 - 1 µg/ml.

Target

  • Function
    Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in stimulating the production of other cytokines such as IL6, IL8 and CSF2, and in regulation of cartilage matrix turnover (PubMed:11591732, PubMed:11591768, PubMed:11574464). Also involved in stimulating the proliferation of peripheral blood mononuclear cells and T-cells and in inhibition of angiogenesis (PubMed:11591732). Plays a role in the induction of neutrophilia in the lungs and in the exacerbation of antigen-induced pulmonary allergic inflammation.
  • Tissue specificity
    Expressed in activated, but not resting, CD4+ T-cells and activated monocytes.
  • Involvement in disease
    Candidiasis, familial, 6
  • Sequence similarities
    Belongs to the IL-17 family.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • CANDF6 antibody
    • Cytokine ML 1 antibody
    • Cytokine ML-1 antibody
    • IL 17F antibody
    • IL 24 antibody
    • IL-17F antibody
    • Il17f antibody
    • IL17F_HUMAN antibody
    • Interleukin 17F antibody
    • Interleukin 24 antibody
    • Interleukin-17F antibody
    • ML 1 antibody
    • ML1 antibody
    • Mutant IL 17F antibody
    • OTTHUMP00000016602 antibody
    see all

References

ab46001 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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