Anti-IL18R Beta antibody (ab47091)

Overview

  • Product nameAnti-IL18R Beta antibody
    See all IL18R Beta primary antibodies
  • Description
    Rabbit polyclonal to IL18R Beta
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide corresponding to a portion of amino acids 50-100 of human IL18R Beta.

  • Positive control
    • human spleen, mouse spleen, RAW cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab47091 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 68 kDa (predicted molecular weight: 68 kDa).

Target

  • FunctionRequired for the high affinity binding of interleukin 18 (IL-18) to its receptor complex (By similarity). Together with IL18R1 mediates IL-18-dependent activation of NF-kappa-B and JNK.
  • Tissue specificityStrongly expressed in peripheral blood leukocytes, spleen, lung, and, to a lesser extent, in colon, but not in any other tissue tested. Strongly expressed in T-cells polarized with IL-12. Specifically coexpressed with IL18R1 in Th1 cells.
  • Sequence similaritiesBelongs to the interleukin-1 receptor family.
    Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 TIR domain.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • IL18RAP antibody
    • Accessory protein like antibody
    • Accessory protein-like antibody
    • AcPL antibody
    • CD218 antigen-like family member B antibody
    • CD218b antibody
    • CDw218b antibody
    • I18RA_HUMAN antibody
    • IL 18RAcP antibody
    • IL 1R accessory protein like antibody
    • IL 1R7 antibody
    • IL 1RAcPL antibody
    • IL-18 receptor accessory protein antibody
    • IL-18R-beta antibody
    • IL-18RAcP antibody
    • IL-18Rbeta antibody
    • IL-1R accessory protein-like antibody
    • IL-1R-7 antibody
    • IL-1R7 antibody
    • IL-1RAcPL antibody
    • IL18RAP antibody
    • IL18Rbeta antibody
    • Interleukin 18 receptor accessory protein antibody
    • Interleukin-1 receptor 7 antibody
    • Interleukin-18 receptor accessory protein antibody
    • Interleukin-18 receptor accessory protein-like antibody
    • Interleukin-18 receptor beta antibody
    • Interleukin-18 receptor beta chain antibody
    see all

Anti-IL18R Beta antibody images

  • All lanes : Anti-IL18R Beta antibody (ab47091) at 2 µg/ml

    Lane 1 : human spleen
    Lane 2 : mouse spleen
    Lane 3 : mouse RAW cell lysate


    Predicted band size : 68 kDa
    Observed band size : 68 kDa
    Additional bands at : 31 kDa,32 kDa,36 kDa. We are unsure as to the identity of these extra bands.

References for Anti-IL18R Beta antibody (ab47091)

ab47091 has not yet been referenced specifically in any publications.

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