Overview

  • Product nameAnti-IL18R Beta antibody [B-B46]
    See all IL18R Beta primary antibodies
  • Description
    Mouse monoclonal [B-B46] to IL18R Beta
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant human IL18R Beta/Fc.

Properties

Applications

Our Abpromise guarantee covers the use of ab47258 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration. Use 10 µl to label 106 cells or 100 µl of whole blood.



ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

Target

  • FunctionRequired for the high affinity binding of interleukin 18 (IL-18) to its receptor complex (By similarity). Together with IL18R1 mediates IL-18-dependent activation of NF-kappa-B and JNK.
  • Tissue specificityStrongly expressed in peripheral blood leukocytes, spleen, lung, and, to a lesser extent, in colon, but not in any other tissue tested. Strongly expressed in T-cells polarized with IL-12. Specifically coexpressed with IL18R1 in Th1 cells.
  • Sequence similaritiesBelongs to the interleukin-1 receptor family.
    Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 TIR domain.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • IL18RAP antibody
    • Accessory protein like antibody
    • Accessory protein-like antibody
    • AcPL antibody
    • CD218 antigen-like family member B antibody
    • CD218b antibody
    • CDw218b antibody
    • I18RA_HUMAN antibody
    • IL 18RAcP antibody
    • IL 1R accessory protein like antibody
    • IL 1R7 antibody
    • IL 1RAcPL antibody
    • IL-18 receptor accessory protein antibody
    • IL-18R-beta antibody
    • IL-18RAcP antibody
    • IL-18Rbeta antibody
    • IL-1R accessory protein-like antibody
    • IL-1R-7 antibody
    • IL-1R7 antibody
    • IL-1RAcPL antibody
    • IL18RAP antibody
    • IL18Rbeta antibody
    • Interleukin 18 receptor accessory protein antibody
    • Interleukin-1 receptor 7 antibody
    • Interleukin-18 receptor accessory protein antibody
    • Interleukin-18 receptor accessory protein-like antibody
    • Interleukin-18 receptor beta antibody
    • Interleukin-18 receptor beta chain antibody
    see all

References for Anti-IL18R Beta antibody [B-B46] (ab47258)

ab47258 has not yet been referenced specifically in any publications.

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