Anti-IL1RA antibody [A71B6D11] (Biotin) (ab25074)

Overview

  • Product nameAnti-IL1RA antibody [A71B6D11] (Biotin)
    See all IL1RA primary antibodies
  • Description
    Mouse monoclonal [A71B6D11] to IL1RA (Biotin)
  • ConjugationBiotin
  • SpecificityRecognises natural and recombinant IL1RA.
  • Tested applicationsELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant human IL1RA

Properties

Applications

Our Abpromise guarantee covers the use of ab25074 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use a concentration of 0.1 - 1 µg/ml.

Target

  • FunctionInhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure.
  • Tissue specificityThe intracellular form of IL1RN is predominantly expressed in epithelial cells.
  • Involvement in diseaseMicrovascular complications of diabetes 4
    Interleukin 1 receptor antagonist deficiency
  • Cellular localizationCytoplasm and Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • DIRA antibody
    • ICIL 1RA antibody
    • ICIL-1RA antibody
    • ICIL1RA antibody
    • IL-1ra antibody
    • IL-1ra3 antibody
    • IL-1RN antibody
    • IL1 inhibitor antibody
    • IL1F3 antibody
    • IL1RA antibody
    • IL1RA_HUMAN antibody
    • IL1RN (IL1F3) antibody
    • IL1RN antibody
    • Interleukin 1 receptor antagonist antibody
    • Interleukin 1 Receptor Antagonist Protein antibody
    • Interleukin-1 receptor antagonist protein antibody
    • Intracellular IL 1 receptor antagonist type II antibody
    • Intracellular interleukin 1 receptor antagonist (icIL 1ra) antibody
    • IRAP antibody
    • MGC10430 antibody
    • MVCD4 antibody
    • Type II interleukin 1 receptor antagonist antibody
    see all

References for Anti-IL1RA antibody [A71B6D11] (Biotin) (ab25074)

ab25074 has not yet been referenced specifically in any publications.

Product Wall

Application ELISA
Sample Human Recombinant protein (Human recombinant IL-1RA from PeproTech)
Specification Human recombinant IL-1RA from PeproTech
Type Sandwich (Detection)
Blocking step BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 1% · Temperature: 20°C
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Submitted Mar 19 2014

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"