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Storage instructions Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage buffer Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
Concentration information loading...
Purity Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 20 kDa.
1/100 - 1/200.
Function Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure.
Tissue specificity The intracellular form of IL1RN is predominantly expressed in epithelial cells.
Involvement in disease Microvascular complications of diabetes 4 Interleukin 1 receptor antagonist deficiency
Cellular localization Cytoplasm and Secreted.
Information by UniProt
ICIL 1RA antibody
Anti-IL1RA antibody images
Western blot - Anti-IL1RA antibody (ab97301)
Anti-IL1RA antibody (ab97301) at 1/1000 dilution + Molt-4 whole cell lysate at 30 µg Predicted band size : 20 kDa
Immunocytochemistry/ Immunofluorescence - Anti-IL1RA antibody (ab97301)
Immunofluorescence analysis of methanol-fixed HeLa, using ab97301 at 1/200 dilution. Lower image costained with Hoechst 33342.
References for Anti-IL1RA antibody (ab97301)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"