Anti-IL1RAPL1 antibody [MM0353-3R16] (ab90453)

Overview

  • Product name
    Anti-IL1RAPL1 antibody [MM0353-3R16]
    See all IL1RAPL1 primary antibodies
  • Description
    Mouse monoclonal [MM0353-3R16] to IL1RAPL1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to the extracellular domain of Human IL1RAPL1

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Protein G purified
  • Purification notes
    The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and filtered through a 0.2 µm filter.
  • Clonality
    Monoclonal
  • Clone number
    MM0353-3R16
  • Isotype
    IgG2
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab90453 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 80 kDa.

Target

  • Function
    May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK.
  • Tissue specificity
    Detected at low levels in heart, skeletal muscle, ovary, skin, amygdala, caudate nucleus, corpus callosum, hippocampus, substantia nigra and thalamus. Detected at very low levels in tonsil, prostate, testis, small intestine, placenta, colon and fetal liver.
  • Involvement in disease
    Defects in IL1RAPL1 are the cause of mental retardation X-linked type 21 (MRX21) [MIM:300143]. Mental retardation is a mental disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.
  • Sequence similarities
    Belongs to the interleukin-1 receptor family.
    Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 TIR domain.
  • Cellular localization
    Cell membrane. Cytoplasm. May localize to the cell body and growth cones of dendrite-like processes.
  • Information by UniProt
  • Database links
  • Alternative names
    • IL 1 RAPL 1 antibody
    • IL 1RAPL 1 antibody
    • IL-1-RAPL-1 antibody
    • IL-1RAPL-1 antibody
    • IL1R8 antibody
    • IL1RAPL 1 antibody
    • IL1RAPL antibody
    • IL1RAPL-1 antibody
    • IL1RAPL1 antibody
    • Interleukin 1 receptor 8 antibody
    • Interleukin 1 receptor accessory protein like 1 antibody
    • Interleukin-1 receptor accessory protein-like 1 antibody
    • IRPL1_HUMAN antibody
    • Mental retardation X linked 10 antibody
    • Mental retardation X linked 21 antibody
    • Mental retardation X linked 34 antibody
    • MRX 21 antibody
    • MRX 34 antibody
    • MRX10 antibody
    • MRX21 antibody
    • MRX34 antibody
    • Oligophrenin 4 antibody
    • Oligophrenin-4 antibody
    • Oligophrenin4 antibody
    • OPHN 4 antibody
    • OPHN4 antibody
    • Three immunoglobulin domain containing IL 1 receptor related 2 antibody
    • Three immunoglobulin domain-containing IL-1 receptor-related 2 antibody
    • TIGIRR 2 antibody
    • TIGIRR-2 antibody
    • TIGIRR2 antibody
    • X linked interleukin 1 receptor accessory protein like 1 antibody
    • X-linked interleukin-1 receptor accessory protein-like 1 antibody
    see all

Anti-IL1RAPL1 antibody [MM0353-3R16] images

  • Anti-IL1RAPL1 antibody [MM0353-3R16] (ab90453) at 1/2000 dilution (Mouse anti human IL-1 R8) + Lysates of human placental tissue

    Predicted band size : 80 kDa
    Observed band size : 80 kDa

References for Anti-IL1RAPL1 antibody [MM0353-3R16] (ab90453)

ab90453 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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