• FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: PBS
  • Concentration information loading...
  • PurityProtein G purified
  • Purification notesThe product is purified by Protein G affinity chromatography.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab10752 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notesELISA: Use at a concentration of 1 µg/ml to detect 0.6 ng/well of recombinant human IL2.
    Neut: Use at a concentration of 0.8 - 8.0 µg/ml.
    WB: Use at a concentration of 2 µg/ml, this detects 5 ng/lane of recombinant human IL2 under reducing conditions and 20 ng/lane under non-reducing conditions.Predicted molecular weight: 19 kDa.

    Anti-Human IL2 is tested for its ability to neutralize the biological activity of recombinant, human IL2 on CTLL2 cells. The ND50 of the antibody is defined as the concentration of antibody resulting in a one-half maximal inhibition of bioactivity of recombinant, human IL2, when IL2 is present at a concentration just high enough to elicit a maximum response.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionProduced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.
    • Involvement in diseaseNote=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17.
    • Sequence similaritiesBelongs to the IL-2 family.
    • Cellular localizationSecreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • Aldesleukin antibody
      • IL 2 antibody
      • IL-2 antibody
      • IL2 antibody
      • IL2_HUMAN antibody
      • Interleukin 2 antibody
      • Interleukin-2 antibody
      • Involved in regulation of T cell clonal expansion antibody
      • Lymphokine antibody
      • OTTHUMP00000164090 antibody
      • POIL2 antibody
      • T Cell Growth Factor antibody
      • T-cell growth factor antibody
      • TCGF antibody
      see all

    References for Anti-IL2 antibody (ab10752)

    This product has been referenced in:
    • Klein M  et al. Repression of cyclic adenosine monophosphate upregulation disarms and expands human regulatory T cells. J Immunol 188:1091-7 (2012). Neutralising ; Human . Read more (PubMed: 22190184) »

    See 1 Publication for this product

    Product Wall

    Thank you for confirming these details and for your cooperation. The details provided enable us to closely monitor the quality of our products. I am sorry this product did not perform as stated on the datasheet and for the inconvenience this has cau...

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    Thank you for forwarding some details of your protocol following our conversation this morning. I understand from the questionnaire you kindly sent that you have only attempted a sandwich ELISA experiment with ab10752. This application has not been tes...

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