Anti-IL2 antibody [AP-MAB0844] (ab80681)

Overview

  • Product nameAnti-IL2 antibody [AP-MAB0844]
    See all IL2 primary antibodies
  • Description
    Rat monoclonal [AP-MAB0844] to IL2
  • Tested applicationsSuitable for: IP, IHC-Fr, Neutralising, Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Recombinant mouse IL2

  • General notes
    Endotoxin Level: Extremely low level of LPS (< 0.002EU/µg IgG).


    ab80681 was produced by in vitro culture, from a hybridoma (mouse myeloma fused with spleen cells from an immunized rat).

Properties

  • FormLyophilised:Reconstitute with 1 ml sterile PBS.
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: PBS
  • Concentration information loading...
  • PurityProtein A purified
  • Purification notesThe IgG fraction of culture supernatant was purified by Protein A affinity chromatography.
  • Primary antibody notesab80681 was produced by in vitro culture, from a hybridoma (mouse myeloma fused with spleen cells from an immunized rat).
  • ClonalityMonoclonal
  • Clone numberAP-MAB0844
  • IsotypeIgG2
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab80681 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP 1/400.
IHC-Fr 1/50.
Neutralising Use at an assay dependent concentration.

ab80681 can be used for neutralizing mouse IL2 in vitro.

Flow Cyt 1/100 - 1/200.

Target

  • FunctionProduced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.
  • Involvement in diseaseNote=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17.
  • Sequence similaritiesBelongs to the IL-2 family.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Aldesleukin antibody
    • IL 2 antibody
    • IL-2 antibody
    • IL2 antibody
    • IL2_HUMAN antibody
    • Interleukin 2 antibody
    • Interleukin-2 antibody
    • Involved in regulation of T cell clonal expansion antibody
    • Lymphokine antibody
    • OTTHUMP00000164090 antibody
    • POIL2 antibody
    • T Cell Growth Factor antibody
    • T-cell growth factor antibody
    • TCGF antibody
    see all

References for Anti-IL2 antibody [AP-MAB0844] (ab80681)

ab80681 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"