Overview

  • Product name
    Anti-IL2 antibody [MQ1-17H12]
    See all IL2 primary antibodies
  • Description
    Rat monoclonal [MQ1-17H12] to IL2
  • Specificity
    ab11448 recognises human IL2 and may be used to detect intracellular IL2 in flow cytometric techniques.
  • Tested applications
    Suitable for: Flow Cyt, ELISAmore details
  • Species reactivity
    Reacts with: Human, Cynomolgus monkey
  • Immunogen

    Recombinant IL2 expressed in E.Coli.

  • General notes
    Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Protein G purified
  • Purification notes
    Purified IgG prepared by affinity chromatography.
  • Clonality
    Monoclonal
  • Clone number
    MQ1-17H12
  • Isotype
    IgG2a
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab11448 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
ELISA
  • Application notes
    ELISA: Use at an assay dependent dilution.
    Flow Cyt: Use at an assay dependent dilution. Membrane permeabilization is required for this application.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.
    • Involvement in disease
      Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17.
    • Sequence similarities
      Belongs to the IL-2 family.
    • Cellular localization
      Secreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • Aldesleukin antibody
      • IL 2 antibody
      • IL-2 antibody
      • IL2 antibody
      • IL2_HUMAN antibody
      • Interleukin 2 antibody
      • Interleukin-2 antibody
      • Involved in regulation of T cell clonal expansion antibody
      • Lymphokine antibody
      • OTTHUMP00000164090 antibody
      • POIL2 antibody
      • T Cell Growth Factor antibody
      • T-cell growth factor antibody
      • TCGF antibody
      see all

    References

    ab11448 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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