Anti-IL2 Receptor alpha antibody (ab61777)

Overview

  • Product name
    Anti-IL2 Receptor alpha antibody
    See all IL2 Receptor alpha primary antibodies
  • Description
    Rabbit polyclonal to IL2 Receptor alpha
  • Specificity
    ab61777 detects endogenous levels of total IL2 Receptor alpha protein.
  • Tested applications
    Suitable for: ELISA, ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic non-phosphopeptide derived from human IL2 Receptor alpha around the phosphorylation site of serine 268 (R-K-S-R-R).

  • Positive control
    • LOVO cell extracts and HeLa cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab61777 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/20000.
ICC/IF 1/500 - 1/1000.
WB 1/500 - 1/1000. Detects a band of approximately 60 kDa (predicted molecular weight: 31 kDa).

Target

  • Function
    Receptor for interleukin-2.
  • Involvement in disease
    Genetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
  • Sequence similarities
    Contains 2 Sushi (CCP/SCR) domains.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Interleukin 2 receptor alpha chain antibody
    • CD25 antibody
    • CD25 antigen antibody
    • IDDM10 antibody
    • IL 2 receptor alpha subunit antibody
    • IL-2 receptor subunit alpha antibody
    • IL-2-RA antibody
    • IL-2R subunit alpha antibody
    • IL2 RA antibody
    • IL2-RA antibody
    • IL2R antibody
    • IL2R, alpha chain antibody
    • IL2RA antibody
    • IL2RA_HUMAN antibody
    • IMD41 antibody
    • Interleukin 2 receptor alpha antibody
    • Interleukin 2 receptor antibody
    • Interleukin-2 receptor subunit alpha antibody
    • p55 antibody
    • t-cell growth factor receptor antibody
    • TAC antibody
    • TAC antigen antibody
    • TCGFR antibody
    see all

Images

  • All lanes : Anti-IL2 Receptor alpha antibody (ab61777) at 1/500 dilution

    Lane 1 : LOVO cell extracts
    Lane 2 : LOVO cell extracts with immunising peptide


    Predicted band size : 31 kDa
    Observed band size : 60 kDa (why is the actual band size different from the predicted?)
  • ab61777 at 1/500 - 1/1000 dilution staining IL2 Receptor alpha in HeLa cells by Immunofluorescence, in the absence or presence of the immunising peptide.

References

ab61777 has not yet been referenced specifically in any publications.

Customer reviews and Q&As


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