Anti-IL2 Receptor alpha antibody [B-B10] (Biotin) (ab34301)

Overview

  • Product nameAnti-IL2 Receptor alpha antibody [B-B10] (Biotin)
    See all IL2 Receptor alpha primary antibodies
  • Description
    Mouse monoclonal [B-B10] to IL2 Receptor alpha (Biotin)
  • ConjugationBiotin
  • SpecificityRecognizes a 55 kDa protein.
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    T cells activated 3 days with PHA (Human)

  • Positive control
    • Purified human T cells activated 3 days in vitro with PHA, Purified human T cells activated 3 days in vitro with PHA.
  • General notesKd 0.4 nM

Properties

Applications

Our Abpromise guarantee covers the use of ab34301 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 10µl for 106 cells. ab18434-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

Target

  • FunctionReceptor for interleukin-2.
  • Involvement in diseaseGenetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
  • Sequence similaritiesContains 2 Sushi (CCP/SCR) domains.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Interleukin 2 receptor alpha chain antibody
    • CD25 antibody
    • CD25 antigen antibody
    • IDDM10 antibody
    • IL 2 receptor alpha subunit antibody
    • IL-2 receptor subunit alpha antibody
    • IL-2-RA antibody
    • IL-2R subunit alpha antibody
    • IL2 RA antibody
    • IL2-RA antibody
    • IL2R antibody
    • IL2R, alpha chain antibody
    • IL2RA antibody
    • IL2RA_HUMAN antibody
    • Interleukin 2 receptor alpha antibody
    • Interleukin 2 receptor antibody
    • Interleukin-2 receptor subunit alpha antibody
    • p55 antibody
    • t-cell growth factor receptor antibody
    • TAC antibody
    • TAC antigen antibody
    • TCGFR antibody
    see all

References for Anti-IL2 Receptor alpha antibody [B-B10] (Biotin) (ab34301)

ab34301 has not yet been referenced specifically in any publications.

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