• Product name
    Anti-IL2 Receptor alpha antibody [PC61]
    See all IL2 Receptor alpha primary antibodies
  • Description
    Rat monoclonal [PC61] to IL2 Receptor alpha
  • Tested applications
    Suitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    IL-2-dependent cytolytic mouse T-cell clone B6.1

  • Positive control
    • Mouse splenocytes, stimulated with 5 ug/ml ConA for three days prior to testing.



Our Abpromise guarantee covers the use of ab86908 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
  • Application notes
    Flow Cyt: Use 0.1-0.25µg for 106 cells.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Receptor for interleukin-2.
    • Involvement in disease
      Genetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
    • Sequence similarities
      Contains 2 Sushi (CCP/SCR) domains.
    • Cellular localization
    • Information by UniProt
    • Database links
    • Alternative names
      • Interleukin 2 receptor alpha chain antibody
      • CD25 antibody
      • CD25 antigen antibody
      • IDDM10 antibody
      • IL 2 receptor alpha subunit antibody
      • IL-2 receptor subunit alpha antibody
      • IL-2-RA antibody
      • IL-2R subunit alpha antibody
      • IL2 RA antibody
      • IL2-RA antibody
      • IL2R antibody
      • IL2R, alpha chain antibody
      • IL2RA antibody
      • IL2RA_HUMAN antibody
      • IMD41 antibody
      • Interleukin 2 receptor alpha antibody
      • Interleukin 2 receptor antibody
      • Interleukin-2 receptor subunit alpha antibody
      • p55 antibody
      • t-cell growth factor receptor antibody
      • TAC antibody
      • TAC antigen antibody
      • TCGFR antibody
      see all

    Anti-IL2 Receptor alpha antibody [PC61] images

    • Flow cytometry analysis in ConA stimulated mouse splenocytes using ab86908 at 0.1 µg per 1x106 cells.

      Shaded histogram represents cells without antibody; green represents isotype control; red represents anti-CD25 antibody.

    References for Anti-IL2 Receptor alpha antibody [PC61] (ab86908)

    This product has been referenced in:
    • Arias RS  et al. RA8, a human anti-CD25 antibody against human Treg cells. Hybridoma (Larchmt) 26:119-30 (2007). Mouse . Read more (PubMed: 17600493) »
    • Uenaka A & Nakayama E Murine leukemia RL male 1 and sarcoma Meth A antigens recognized by cytotoxic T lymphocytes (CTL). Cancer Sci 94:931-6 (2003). Mouse . Read more (PubMed: 14611667) »

    See all 2 Publications for this product

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