Anti-IL2 Receptor alpha (phospho S268) antibody (ab61798)

Overview

  • Product nameAnti-IL2 Receptor alpha (phospho S268) antibody
    See all IL2 Receptor alpha primary antibodies
  • Description
    Rabbit polyclonal to IL2 Receptor alpha (phospho S268)
  • SpecificityDetects endogenous levels of IL2 Receptor alpha only when phosphorylated at serine 268.
  • Tested applicationsSuitable for: ICC/IF, WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic phosphopeptide derived from human IL2 Receptor alpha around the phosphorylation site of serine 268 (R-K-SP-R-R). (Swiss-Prot P01589).

  • Positive control
    • HeLa cells, extracts from LOVO cells

Properties

Applications

Our Abpromise guarantee covers the use of ab61798 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/500 - 1/1000.
WB 1/500 - 1/1000. Detects a band of approximately 60 kDa (predicted molecular weight: 31 kDa).
ELISA 1/10000.

Target

  • FunctionReceptor for interleukin-2.
  • Involvement in diseaseGenetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
  • Sequence similaritiesContains 2 Sushi (CCP/SCR) domains.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Interleukin 2 receptor alpha chain antibody
    • CD25 antibody
    • CD25 antigen antibody
    • IDDM10 antibody
    • IL 2 receptor alpha subunit antibody
    • IL-2 receptor subunit alpha antibody
    • IL-2-RA antibody
    • IL-2R subunit alpha antibody
    • IL2 RA antibody
    • IL2-RA antibody
    • IL2R antibody
    • IL2R, alpha chain antibody
    • IL2RA antibody
    • IL2RA_HUMAN antibody
    • Interleukin 2 receptor alpha antibody
    • Interleukin 2 receptor antibody
    • Interleukin-2 receptor subunit alpha antibody
    • p55 antibody
    • t-cell growth factor receptor antibody
    • TAC antibody
    • TAC antigen antibody
    • TCGFR antibody
    see all

Anti-IL2 Receptor alpha (phospho S268) antibody images

  • All lanes : Anti-IL2 Receptor alpha (phospho S268) antibody (ab61798) at 1/500 dilution

    Lane 1 : extracts from LOVO cells
    Lane 2 : extracts from LOVO cells with immunizing peptide


    Predicted band size : 31 kDa
    Observed band size : 60 kDa (why is the actual band size different from the predicted?)
  • Ab61798 at 1/500 dilution staining HeLa cells without (left) and with (right) immunizing peptide.

References for Anti-IL2 Receptor alpha (phospho S268) antibody (ab61798)

ab61798 has not yet been referenced specifically in any publications.

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