Anti-IL2 Receptor beta antibody [5H4] (Phycoerythrin) (ab95585)

Overview

  • Product nameAnti-IL2 Receptor beta antibody [5H4] (Phycoerythrin)
    See all IL2 Receptor beta primary antibodies
  • Description
    Rat monoclonal [5H4] to IL2 Receptor beta (Phycoerythrin)
  • ConjugationPhycoerythrin. Ex: 488nm, Em: 575nm
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Rat myeloma cells transfected with a truncated mouse IL2 Receptor beta cDNA

  • Positive control
    • BALB/c splenocytes
  • General notes


    Binding of IL2 to IL2 receptor beta is not inhibited by the ab95585.

Properties

Applications

Our Abpromise guarantee covers the use of ab95585 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 0.125µg for 105-8 cells.

Target

  • FunctionReceptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
  • Sequence similaritiesBelongs to the type I cytokine receptor family. Type 4 subfamily.
    Contains 1 fibronectin type-III domain.
  • DomainThe WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
    The box 1 motif is required for JAK interaction and/or activation.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD122 antibody
    • CD122 antigen antibody
    • High affinity IL 2 receptor beta subunit antibody
    • High affinity IL 2 receptor subunit beta antibody
    • High affinity IL-2 receptor subunit beta antibody
    • IL-2 receptor subunit beta antibody
    • IL-2R subunit beta antibody
    • IL-2RB antibody
    • IL15RB antibody
    • IL2 receptor antibody
    • IL2RB antibody
    • IL2RB_HUMAN antibody
    • Interleukin 2 receptor beta antibody
    • Interleukin-2 receptor subunit beta antibody
    • P70 75 antibody
    • P70-75 antibody
    • P7075 antibody
    • p75 antibody
    see all

Anti-IL2 Receptor beta antibody [5H4] (Phycoerythrin) images

  • Staining of BALB/c splenocytes with staining buffer (autofluorescence) (open histogram) or 0.125 µg of ab95585 (filled histogram). Total viable cells were used for analysis.

References for Anti-IL2 Receptor beta antibody [5H4] (Phycoerythrin) (ab95585)

ab95585 has not yet been referenced specifically in any publications.

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