Anti-IL2 Receptor beta antibody [L316] (Phycoerythrin) (ab33958)

Overview

  • Product nameAnti-IL2 Receptor beta antibody [L316] (Phycoerythrin)
    See all IL2 Receptor beta primary antibodies
  • Description
    Mouse monoclonal [L316] to IL2 Receptor beta (Phycoerythrin)
  • ConjugationPhycoerythrin. Ex: 488nm, Em: 575nm
  • Specificityab33958 recognises CD122 the 80kD Beta subunit of IL2R, which is shared by the IL15 receptor.
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Rat
  • Immunogen

    Rat CRNK cells and rat IL2 Receptor beta cDNA-transfected mouse L929 cell line.

Properties

Applications

Our Abpromise guarantee covers the use of ab33958 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
  • Application notesFlow Cyt: Use 10ul to label 106 cells in 100ul.
    Note: An incubation time of 4 hours is recommended for optimum staining

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionReceptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
    • Sequence similaritiesBelongs to the type I cytokine receptor family. Type 4 subfamily.
      Contains 1 fibronectin type-III domain.
    • DomainThe WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
      The box 1 motif is required for JAK interaction and/or activation.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • CD122 antibody
      • CD122 antigen antibody
      • High affinity IL 2 receptor beta subunit antibody
      • High affinity IL 2 receptor subunit beta antibody
      • High affinity IL-2 receptor subunit beta antibody
      • IL-2 receptor subunit beta antibody
      • IL-2R subunit beta antibody
      • IL-2RB antibody
      • IL15RB antibody
      • IL2 receptor antibody
      • IL2RB antibody
      • IL2RB_HUMAN antibody
      • Interleukin 2 receptor beta antibody
      • Interleukin-2 receptor subunit beta antibody
      • P70 75 antibody
      • P70-75 antibody
      • P7075 antibody
      • p75 antibody
      see all

    References for Anti-IL2 Receptor beta antibody [L316] (Phycoerythrin) (ab33958)

    This product has been referenced in:
    • Park JH  et al. Identification and cellular distribution of the rat interleukin-2 receptor beta chain: induction of the IL-2R alpha- beta+ phenotype by major histocompatibility complex class I recognition during T cell development in vivo and by T cell receptor stimulation of CD4+8+ immature thymocytes in vitro. Eur J Immunol 26:2371-5 (1996). Read more (PubMed: 8898947) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"