Anti-IL2 Receptor beta antibody [TM-beta1] (Phycoerythrin) (ab95774)

Overview

  • Product nameAnti-IL2 Receptor beta antibody [TM-beta1] (Phycoerythrin)
    See all IL2 Receptor beta primary antibodies
  • Description
    Rat monoclonal [TM-beta1] to IL2 Receptor beta (Phycoerythrin)
  • ConjugationPhycoerythrin. Ex: 488nm, Em: 575nm
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Rat T cell line expressing Mouse IL2 Receptor beta.

  • Positive control
    • Mouse splenocyte suspensions
  • General notes


    High affinity binding of IL2 to the IL2 receptor is inhibited by ab95774.

Properties

Applications

Our Abpromise guarantee covers the use of ab95774 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 0.06-0.125µg for 105-8 cells. A final volume of 100 µL is recommended for staining the cell sample.

Target

  • FunctionReceptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
  • Sequence similaritiesBelongs to the type I cytokine receptor family. Type 4 subfamily.
    Contains 1 fibronectin type-III domain.
  • DomainThe WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
    The box 1 motif is required for JAK interaction and/or activation.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD122 antibody
    • CD122 antigen antibody
    • High affinity IL 2 receptor beta subunit antibody
    • High affinity IL 2 receptor subunit beta antibody
    • High affinity IL-2 receptor subunit beta antibody
    • IL-2 receptor subunit beta antibody
    • IL-2R subunit beta antibody
    • IL-2RB antibody
    • IL15RB antibody
    • IL2 receptor antibody
    • IL2RB antibody
    • IL2RB_HUMAN antibody
    • Interleukin 2 receptor beta antibody
    • Interleukin-2 receptor subunit beta antibody
    • P70 75 antibody
    • P70-75 antibody
    • P7075 antibody
    • p75 antibody
    see all

Anti-IL2 Receptor beta antibody [TM-beta1] (Phycoerythrin) images

  • Staining of C57BL/6 splenocytes with Anti-Mouse NK1.1 APC and 0.06 µg of Rat IgG2b ? Isotype Control PE (left) or 0.06 µg of ab95774 (right).
    Total viable cells were used for analysis.

References for Anti-IL2 Receptor beta antibody [TM-beta1] (Phycoerythrin) (ab95774)

This product has been referenced in:
  • French JD  et al. {gamma}{delta} T cell homeostasis is established in competition with {alpha}{beta} T cells and NK cells. Proc Natl Acad Sci U S A 102:14741-6 (2005). Read more (PubMed: 16203967) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"