Overview

  • Product name
    Anti-IL20RB antibody [20RNTC]
    See all IL20RB primary antibodies
  • Description
    Rat monoclonal [20RNTC] to IL20RB
  • Specificity
    ab95824 recognizes Mouse and Human IL20RB in either of its two heterodimeric complexes formed by pairing with IL-20RA or IL-22RA1
  • Tested applications
    Suitable for: Flow Cyt, ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Recombinant mIL20RB protein (extracellular domain)

  • Positive control
    • Fixed and permeabilized A375 cells

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: 1% PBS, pH 7.2
  • Concentration information loading...
  • Purity
    Protein G purified
  • Clonality
    Monoclonal
  • Clone number
    20RNTC
  • Isotype
    IgG2a
  • Light chain type
    kappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab95824 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use a concentration of 1 - 10 µg/ml. ab18450-Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
ICC/IF Use a concentration of 1 - 10 µg/ml.
WB Use at an assay dependent concentration. PubMed: 23441190

Target

  • Function
    The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24.
  • Tissue specificity
    Widely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin.
  • Sequence similarities
    Belongs to the type II cytokine receptor family.
    Contains 2 fibronectin type-III domains.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • DIRS1 antibody
    • Fibronectin type III domain containing 6 antibody
    • FNDC6 antibody
    • I20RB_HUMAN antibody
    • IL 20R beta antibody
    • IL 20R2 antibody
    • IL-20 receptor subunit beta antibody
    • IL-20R-beta antibody
    • IL-20R2 antibody
    • IL-20RB antibody
    • IL20RB antibody
    • Interleukin 20 receptor beta antibody
    • Interleukin 20 receptor beta chain precursor antibody
    • Interleukin 20 receptor II antibody
    • Interleukin-20 receptor subunit beta antibody
    • MGC34923 antibody
    see all

Images

  • Immunofluorescent microscopy of fixed and permeabilized A375 cells using 10 µg/ml of ab95824 (right) or Rat IgG2a ? Isotype Control Purified (left) followed by Anti-Rat IgG Biotin and then Streptavidin FITC.
  • Mouse IL-20Rb-GFP 293 transfectants stained with 0.25ug ab95824 + anti-rat IgG PE

References

This product has been referenced in:
  • He B  et al. A remote cis-acting variant at 3q links glomerular NCK1 to diabetic nephropathy. PLoS One 8:e56414 (2013). WB ; Mouse . Read more (PubMed: 23441190) »
  • Hsing CH  et al. Upregulated IL-19 in breast cancer promotes tumor progression and affects clinical outcome. Clin Cancer Res 18:713-25 (2012). ICC/IF . Read more (PubMed: 22186257) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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