Anti-IL22 RA2 antibody [MM0397-6G47] (ab90937)

Overview

  • Product name
    Anti-IL22 RA2 antibody [MM0397-6G47]
    See all IL22 RA2 primary antibodies
  • Description
    Mouse monoclonal [MM0397-6G47] to IL22 RA2
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length Human IL22 RA2

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Protein G purified
  • Purification notes
    The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and filtered through a 0.2 µm filter.
  • Clonality
    Monoclonal
  • Clone number
    MM0397-6G47
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab90937 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 31 kDa.

Target

  • Function
    Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses.
    Isoform 1 may play a role in establishing and maintaining successful pregnancy.
  • Tissue specificity
    Expressed in placenta, spleen, breast, skin and lung. Also detected in intestinal tract, testis, brain, heart and thymus. No expression found in prostate, bladder, kidney, ovary, muscle, bone marrow, liver and uterus. Isoform 1 is expressed only in placenta. Isoform 2 is expressed in placenta and breast and at lower level in spleen, skin, thymus and stomach.
  • Sequence similarities
    Belongs to the type II cytokine receptor family.
    Contains 3 fibronectin type-III domains.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • IL 22BP antibody
    • IL 22RA2 antibody
    • IL22RA2 antibody
    • Class II cytokine receptor antibody
    • CRF2 10 antibody
    • CRF2 S1 antibody
    • CRF2-10 antibody
    • CRF2-S1 antibody
    • CRF2X antibody
    • Cytokine receptor class II member 10 antibody
    • Cytokine receptor class-II member 10 antibody
    • Cytokine receptor family 2 member 10 antibody
    • Cytokine receptor family type 2 antibody
    • Cytokine receptor family type 2 soluble 1 antibody
    • I22R2_HUMAN antibody
    • IL 22 receptor subunit alpha 2 antibody
    • IL 22R alpha 2 antibody
    • IL-22 receptor subunit alpha-2 antibody
    • IL-22BP antibody
    • IL-22R-alpha-2 antibody
    • IL-22RA2 antibody
    • IL22BP antibody
    • IL22R alpha 2 antibody
    • Il22ra2 antibody
    • Interleukin 22 binding protein antibody
    • Interleukin 22 Receptor alpha 2 antibody
    • Interleukin-22 receptor subunit alpha-2 antibody
    • Interleukin-22-binding protein antibody
    • MGC150509 antibody
    • MGC150510 antibody
    • soluble 1 antibody
    • ZcytoR16 antibody
    see all

References for Anti-IL22 RA2 antibody [MM0397-6G47] (ab90937)

ab90937 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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