• Product nameAnti-IL23 P19 antibody
    See all IL23 P19 primary antibodies
  • Description
    Rabbit polyclonal to IL23 P19
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Horse, Cow, Cat, Deer
  • Immunogen

    Synthetic peptide conjugated to KLH derived from within residues 100 to the C-terminus of Human IL23 P19.

    (Peptide available as ab91437.)

  • Positive control
    • This antibody gave a positive signal in the following whole cell lysates: Raji; Jurkat; Ramos; HeLa; A431.


Associated products


Our Abpromise guarantee covers the use of ab80893 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 20 kDa (predicted molecular weight: 20 kDa).


  • FunctionAssociates with IL12B to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to an heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
  • Tissue specificitySecreted by activated dendritic and phagocytic cells and keratinocytes. Also expressed by dermal Langerhans cells (at protein level).
  • Sequence similaritiesBelongs to the IL-6 superfamily.
  • Developmental stageExpressed by newborns dendritic cells.
  • Cellular localizationSecreted. Secreted upon association with IL12B.
  • Information by UniProt
  • Database links
  • Alternative names
    • IL-23 subunit alpha antibody
    • IL-23-A antibody
    • IL-23p19 antibody
    • Il23a antibody
    • IL23A_HUMAN antibody
    • IL23P19 antibody
    • Interleukin 23 alpha subunit p19 antibody
    • Interleukin 23 P19 subunit antibody
    • Interleukin-23 subunit alpha antibody
    • Interleukin-23 subunit p19 antibody
    • interleukin-six, G-CSF related factor antibody
    • JKA3 induced upon T cell activation antibody
    • P19 antibody
    • SGRF antibody
    see all

Anti-IL23 P19 antibody images

  • All lanes : Anti-IL23 antibody (ab80893) at 1 µg/ml

    Lane 1 : Raji (Human Burkitt's lymphoma cell line) Whole Cell Lysate
    Lane 2 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell Lysate
    Lane 3 : Ramos (Human Burkitt's lymphoma cell line) Whole Cell Lysate
    Lane 4 : HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate
    Lane 5 : A431 (Human epithelial carcinoma cell line) Whole Cell Lysate

    Lysates/proteins at 20 µg per lane.

    Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
    developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 20 kDa
    Observed band size : 20 kDa
    Additional bands at : 10 kDa,150 kDa,37 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 20 minutes

References for Anti-IL23 P19 antibody (ab80893)

ab80893 has not yet been referenced specifically in any publications.

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