Overview

  • Product name
  • Description
    Rabbit polyclonal to IL26
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    KLH conjugated synthetic peptide corresponding to a region between amino acid 94 - 124 from the central region of Human il26 (UniProt ID: Q9NPH9).

  • Positive control
    • HL60 cell line lysates

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab102977 is purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab102977 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 20 kDa.

Target

  • Function
    May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin.
  • Tissue specificity
    Expressed in HVS transformed T-cells but not other T-cell lines or primary stimulated T-cells. Expressed in colonic T cells including Th17 inflammatory T cells; the expression is significantly increased in serum of patients with Crohn's disease (at protein level).
  • Sequence similarities
    Belongs to the IL-10 family.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • AK155 antibody
    • IL 26 antibody
    • IL-26 antibody
    • IL26 antibody
    • IL26_HUMAN antibody
    • Interleukin 26 antibody
    • Interleukin-26 antibody
    • Protein AK155 antibody
    see all

Images

  • Anti-IL26 antibody (ab102977) at 1/100 dilution + HL60 cell line lysates at 35 µg

    Predicted band size : 20 kDa

References

This product has been referenced in:
  • Che KF  et al. Interleukin-26 Production in Human Primary Bronchial Epithelial Cells in Response to Viral Stimulation: Modulation by Th17 cytokines. Mol Med 23:N/A (2017). WB ; Human . Read more (PubMed: 28853490) »
  • Reemann P  et al. Expression of class II cytokine genes in children's skin. Acta Derm Venereol 94:386-92 (2014). Read more (PubMed: 24284923) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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