Overview

  • Product name
    Anti-IL28 Receptor alpha antibody
    See all IL28 Receptor alpha primary antibodies
  • Description
    Goat polyclonal to IL28 Receptor alpha
  • Specificity
    This antibody recognizes the N-terminus of mouse CRF-2-12 (IL-28 receptor alpha) protein. This antibody is likely to recognize rat CRF-2-12 (IL-28 receptor alpha) protein due to sequence similiarity. The peptide sequence is < 50 % identical to other sequences in GenBank.
  • Tested applications
    Suitable for: ELISA, ICC, Flow Cyt, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat
  • Immunogen

    Synthetic peptide:

    LPGLGSPPNVTYFVTYQSYIKTGWRPVEH

    , corresponding to N terminal amino acids 44-72 of Mouse IL28 Receptor alpha.

  • Positive control
    • Mouse spleen.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.1% Sodium Azide
    Constituents: 140mM Sodium chloride, 10mM Potassium phosphate. pH 7.2
  • Concentration information loading...
  • Purity
    Protein G purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab18567 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/100000.
ICC 1/300.
Flow Cyt Use at an assay dependent concentration. ab37373-Goat polyclonal IgG, is suitable for use as an isotype control with this antibody.
IHC-P 1/300.

Target

  • Relevance
    IL28RA is a class II cytokine receptor that interacts with IL10RB to bind IL28A, IL28B, and IL29, which are related to type I interferons. These ligands play a critical role in response to microbial challenge and activate the JAK/STAT signaling system. It heterodimers with IL10RB. There are 4 isoforms as result of alternative splicing. It is widely expressed. IL28RA belongs to the type II cytokine receptor family, and contains 1 fibronectin type III domain.
  • Cellular localization
    Membrane; Single-pass type I membrane protein
  • Database links
  • Alternative names
    • Class II cytokine receptor CRF2/12 antibody
    • CRF2-12 antibody
    • CRF2/12 antibody
    • Cytokine receptor class-II member 12 antibody
    • Cytokine receptor family 2 member 12 antibody
    • IFN lambda R1 antibody
    • IFN-lambda receptor 1 antibody
    • IFNLR antibody
    • IFNLR1 antibody
    • IL-28 receptor subunit alpha antibody
    • il-28r1 antibody
    • IL28R alpha antibody
    • IL28RA antibody
    • Interferon lambda receptor antibody
    • Interferon lambda receptor 1 antibody
    • interleukin 28 alpha receptor antibody
    • interleukin 28 receptor A antibody
    • Interleukin 28 receptor alpha chain antibody
    • interleukin 28 receptor, alpha (interferon, lambda receptor) antibody
    • Interleukin 28 receptor, alpha antibody
    • interleukin or cytokine receptor 2 antibody
    • Interleukin-28 receptor subunit alpha antibody
    • LICR2 antibody
    • Likely interleukin or cytokine receptor 2 antibody
    see all

Images

  • ab18567 at a dilution of 1/300, staining IL28 receptor alpha in mouse spleen section by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).

References

This product has been referenced in:
  • Numasaki M  et al. IL-28 elicits antitumor responses against murine fibrosarcoma. J Immunol 178:5086-98 (2007). Flow Cyt ; Mouse . Read more (PubMed: 17404291) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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