Overview

  • Product name
  • Description
    Rabbit polyclonal to IL28A
  • Tested applications
    Suitable for: WB, Indirect ELISA, Sandwich ELISAmore details
  • Species reactivity
    Reacts with: Recombinant fragment
    Predicted to work with: Human
  • Immunogen

    Highly pure (>98%) recombinant Human IL28A

Properties

  • Form
    Lyophilised:Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer
    Preservative: None
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab109820 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 22 kDa. The detection limit for recombinant Human IL28A is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.
Indirect ELISA Use a concentration of 0.5 - 2 µg/ml. ab109820 in conjunction with compatible secondary reagents, allows the detection of at least 0.2 - 0.4 ng/well of recombinant Human IL28A.
Sandwich ELISA Use a concentration of 0.5 - 2 µg/ml. Can be paired for Sandwich ELISA with Rabbit polyclonal to IL28A (Biotin) (ab84239). ab109820 in conjunction with ab84239 as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant Human IL28A.

Target

  • Function
    Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
  • Sequence similarities
    Belongs to the IL-28/IL-29 family.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cytokine ZCYTO20 antibody
    • IFN-lambda-2 antibody
    • IFNL2 antibody
    • IL-28A antibody
    • IL28A antibody
    • IL28A_HUMAN antibody
    • Interferon lambda 2 antibody
    • Interferon lambda-2 antibody
    • interleukin 28A (interferon, lambda 2) antibody
    • Interleukin 28A antibody
    • Interleukin-28A antibody
    • ZCYTO20 antibody
    see all

References

This product has been referenced in:

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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