Anti-IL2RA antibody [PC61.5.3] (FITC) (ab112163)

Overview

  • Product nameAnti-IL2RA antibody [PC61.5.3] (FITC)
    See all IL2RA primary antibodies
  • Description
    Rat monoclonal [PC61.5.3] to IL2RA (FITC)
  • ConjugationFITC. Ex: 493nm, Em: 528nm
  • Tested applicationsSuitable for: IP, Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    B6.1 CTL Cell line

  • Positive control
    • Mouse Strain: BALB/c, T Cell Blasts (Con A activated)

Properties

Applications

Our Abpromise guarantee covers the use of ab112163 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at an assay dependent concentration.
Flow Cyt Use 1µg for 106 cells. ab18404-Rat monoclonal IgG1, is suitable for use as an isotype control with this antibody.

Target

  • FunctionReceptor for interleukin-2.
  • Involvement in diseaseGenetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
  • Sequence similaritiesContains 2 Sushi (CCP/SCR) domains.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD25 antibody
    • IDDM10 antibody
    • IL 2 RA antibody
    • IL 2 receptor subunit alpha antibody
    • IL 2R alpha chain antibody
    • IL 2R subunit alpha antibody
    • IL-2 receptor subunit alpha antibody
    • IL-2-RA antibody
    • IL-2R subunit alpha antibody
    • IL2 RA antibody
    • IL2 Receptor alpha antibody
    • IL2 receptor subunit alpha antibody
    • IL2-RA antibody
    • IL2R alpha chain antibody
    • IL2R antibody
    • IL2R subunit alpha antibody
    • IL2RA antibody
    • IL2RA_HUMAN antibody
    • Interleukin 2 receptor alpha chain antibody
    • interleukin 2 receptor subunit alpha antibody
    • Interleukin 2 receptor, alpha antibody
    • Interleukin-2 receptor subunit alpha antibody
    • Ly 43 antibody
    • Ly43 antibody
    • OTTHUMP00000019030 antibody
    • OTTHUMP00000019031 antibody
    • OTTHUMP00000019032 antibody
    • p55 antibody
    • p55 chain antibody
    • T Cell Growth Factor Receptor antibody
    • TAC antigen antibody
    • TCGFR antibody
    see all

Anti-IL2RA antibody [PC61.5.3] (FITC) images

  • Cell Source: T Cell Blasts (Con A Activated)
    Percentage of cells stained above control: 90.9%, ab112163 at a concentration of 1.0µg/106

References for Anti-IL2RA antibody [PC61.5.3] (FITC) (ab112163)

ab112163 has not yet been referenced specifically in any publications.

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