Anti-IL3RA/CD123 antibody [6H6] (ab21562)
Key features and details
- Mouse monoclonal [6H6] to IL3RA/CD123
- Suitable for: Flow Cyt
- Reacts with: Human
- Isotype: IgG1
Related conjugates and formulations
Overview
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Product name
Anti-IL3RA/CD123 antibody [6H6]
See all IL3RA/CD123 primary antibodies -
Description
Mouse monoclonal [6H6] to IL3RA/CD123 -
Host species
Mouse -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Human -
Immunogen
Tissue, cells or virus corresponding to Human IL3RA/CD123.
Database link: P26951 -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
6H6 -
Isotype
IgG1 -
Light chain type
kappa -
Research areas
Associated products
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Alternative Versions
- PerCP/Cy5.5® Anti-IL3RA/CD123 antibody [6H6] (ab157332)
- Biotin Anti-IL3RA/CD123 antibody [6H6] (ab21560)
- PE/Cy5® Anti-IL3RA/CD123 antibody [6H6] (ab232697)
- PE/Cy7® Anti-IL3RA/CD123 antibody [6H6] (ab233585)
- PE Anti-IL3RA/CD123 antibody [6H6] (ab93523)
- APC Anti-IL3RA/CD123 antibody [6H6] (ab95781)
- FITC Anti-IL3RA/CD123 antibody [6H6] (ab95782)
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Compatible Secondaries
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Conjugation kits
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab21562 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
Flow Cyt | (1) |
Use 1µg for 106 cells.
100 µl volume or 100 µl of whole blood. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
Notes |
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Flow Cyt
Use 1µg for 106 cells. 100 µl volume or 100 µl of whole blood. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
Target
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Function
This is a receptor for interleukin-3. -
Sequence similarities
Belongs to the type I cytokine receptor family. Type 5 subfamily. -
Domain
The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
The box 1 motif is required for JAK interaction and/or activation. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 3563 Human
- Omim: 308385 Human
- Omim: 430000 Human
- SwissProt: P26951 Human
- Unigene: 632790 Human
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Alternative names
- CD123 antibody
- CD123 antigen antibody
- hIL 3Ra antibody
see all
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab21562 has been referenced in 2 publications.
- Chen L et al. LncRNA MAGI2-AS3 inhibits the self-renewal of leukaemic stem cells by promoting TET2-dependent DNA demethylation of the LRIG1 promoter in acute myeloid leukaemia. RNA Biol 17:784-793 (2020). PubMed: 32174258
- Herling M et al. TCL1 expression in plasmacytoid dendritic cells (DC2s) and the related CD4+ CD56+ blastic tumors of skin. Blood 101:5007-9 (2003). PubMed: 12576313