The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesFlow Cyt: Use 1µg for 106 cells in 100µl total staining volume.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionHigh affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.
Sequence similaritiesBelongs to the type I cytokine receptor family. Type 4 subfamily. Contains 2 fibronectin type-III domains.
DomainThe WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding. The box 1 motif is required for JAK interaction and/or activation.
Sstaining of normal Human peripheral blood cells using ab90971 at 1 µg for 106 cells in 100 µl volume (blue histogram) or a control antibody (open histogram). Cells in the monocyte population were used for analysis.
References for Anti-IL3RB antibody [1C1] (ab90971)
has not yet been referenced specifically in any publications.
Publishing research using ab90971? Please let us know so that we can cite the reference in this datasheet.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"