Overview

  • Product name
    Anti-IL3RB antibody [RM0112-42A7]
    See all IL3RB primary antibodies
  • Description
    Rat monoclonal [RM0112-42A7] to IL3RB
  • Specificity
    This antibody detects mouse IL3RB, but not IL3RA in Western blotting.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Mouse recombinant protein of the extracellular domain of IL3RB.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Protein A purified
  • Purification notes
    The IgG fraction of culture supernatant was purified by Protein A affinity chromatography
  • Clonality
    Monoclonal
  • Clone number
    RM0112-42A7
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab86743 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 97 kDa.

Target

  • Function
    High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.
  • Sequence similarities
    Belongs to the type I cytokine receptor family. Type 4 subfamily.
    Contains 2 fibronectin type-III domains.
  • Domain
    The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
    The box 1 motif is required for JAK interaction and/or activation.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • /granulocyte-macrophage colony-stimulating factor receptor, beta antibody
    • Beta-C antibody
    • CD131 antibody
    • CDw131 antibody
    • Colony stimulating factor 2 receptor beta antibody
    • Colony stimulating factor 2 receptor beta low affinity (granulocyte macrophage) antibody
    • Common beta chain antibody
    • Csf2rb antibody
    • Cytokine receptor common beta chain antibody
    • Cytokine receptor common beta chain precursor (CDw131 antigen) antibody
    • Cytokine receptor common subunit beta antibody
    • GM CSF/IL 3/IL 5 receptor common beta chain antibody
    • GM-CSF/IL-3/IL-5 receptor common beta subunit antibody
    • IL3RB antibody
    • IL3RB_HUMAN antibody
    • IL5RB antibody
    • Interleukin 3 receptor, beta antibody
    • Interleukin 3 receptor/granulocyte macrophage colony stimulating factor 3 receptor beta (high affinity) antibody
    • Interleukin 5 receptor, beta antibody
    • SMDP5 antibody
    • stimulating factor 3 receptor, beta (high affinity) antibody
    see all

References

This product has been referenced in:
  • Egea L  et al. GM-CSF produced by nonhematopoietic cells is required for early epithelial cell proliferation and repair of injured colonic mucosa. J Immunol 190:1702-13 (2013). Read more (PubMed: 23325885) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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