Overview

  • Product nameAnti-IL4 antibody [EPR1118Y]
    See all IL4 primary antibodies
  • Description
    Rabbit monoclonal [EPR1118Y] to IL4
  • Tested applicationsSuitable for: WB, ICC/IFmore details
    Unsuitable for: Flow Cyt,IHC-P or IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A synthetic peptide corresponding to residues in human IL4

  • Positive control
    • Human tonsil lysate
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

Properties

Applications

Our Abpromise guarantee covers the use of ab62351 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/2000. Predicted molecular weight: 17 kDa.
ICC/IF 1/500.
  • Application notesIs unsuitable for Flow Cyt,IHC-P or IP.
  • Target

    • FunctionParticipates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.
    • Involvement in diseaseGenetic variations in IL4 may be a cause of susceptibility to ischemic stroke (ISCHSTR) [MIM:601367]; also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors.
    • Sequence similaritiesBelongs to the IL-4/IL-13 family.
    • Cellular localizationSecreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • B cell growth factor 1 antibody
      • B cell IgG differentiation factor antibody
      • B Cell Stimulatory Factor 1 antibody
      • B-cell stimulatory factor 1 antibody
      • BCGF 1 antibody
      • BCGF1 antibody
      • Binetrakin antibody
      • BSF-1 antibody
      • BSF1 antibody
      • IGG1 induction factor antibody
      • IL 4 antibody
      • IL-4 antibody
      • IL4 antibody
      • IL4_HUMAN antibody
      • Il4e12 antibody
      • Interleukin 4 antibody
      • Interleukin 4 variant 2 antibody
      • Interleukin 4, isoform 1 antibody
      • Interleukin-4 antibody
      • Lymphocyte stimulatory factor 1 antibody
      • MGC79402 antibody
      • Pitrakinra antibody
      see all

    Anti-IL4 antibody [EPR1118Y] images

    • Immunocytochemistry/Immunofluorescence analysis of RAMOS (human Burkitt's lymphoma) labelling IL4 with purified ab62351 at 1/500. Cells were fixed with 100% methanol. An Alexa Fluor® 488-conjugated goat anti-rabbit IgG (1/1000) was used as the secondary antibody (Ab150077). Nuclei counterstained with DAPI (blue).

      Control: PBS only

    • Anti-IL4 antibody [EPR1118Y] (ab62351) at 1/2000 dilution + Human tonsil lysate at 10 µg

      Secondary
      goat anti rabbit HRP at 1/2000 dilution

      Predicted band size : 17 kDa
      Observed band size : 14 kDa (why is the actual band size different from the predicted?)

    References for Anti-IL4 antibody [EPR1118Y] (ab62351)

    ab62351 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab62351.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"