Overview

  • Product name
    Anti-IL4 antibody [QS-4]
    See all IL4 primary antibodies
  • Description
    Mouse monoclonal [QS-4] to IL4
  • Specificity
    ab25114 recognises both natural and recombinant IL-4 in vitro.
  • Tested applications
    Suitable for: ELISA, ELISpot, Neutralisingmore details
  • Species reactivity
    Reacts with: Monkey
  • Immunogen

    Full length native protein, monkey (purified)

Properties

Applications

Our Abpromise guarantee covers the use of ab25114 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
ELISpot
Neutralising
  • Application notes
    ELISA: Use at an assay dependent dilution.
    ELISPOT: Use at an assay dependent dilution.
    Neut: Use at an assay dependent dilution; inhibits natural IL4 induced IgE production and inhibits recombinant IL4 induced T cells proliferation.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.
    • Involvement in disease
      Genetic variations in IL4 may be a cause of susceptibility to ischemic stroke (ISCHSTR) [MIM:601367]; also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors.
    • Sequence similarities
      Belongs to the IL-4/IL-13 family.
    • Cellular localization
      Secreted.
    • Information by UniProt
    • Alternative names
      • B cell growth factor 1 antibody
      • B cell IgG differentiation factor antibody
      • B Cell Stimulatory Factor 1 antibody
      • B-cell stimulatory factor 1 antibody
      • BCGF 1 antibody
      • BCGF1 antibody
      • Binetrakin antibody
      • BSF-1 antibody
      • BSF1 antibody
      • IGG1 induction factor antibody
      • IL 4 antibody
      • IL-4 antibody
      • IL4 antibody
      • IL4_HUMAN antibody
      • Il4e12 antibody
      • Interleukin 4 antibody
      • Interleukin 4 variant 2 antibody
      • Interleukin 4, isoform 1 antibody
      • Interleukin-4 antibody
      • Lymphocyte stimulatory factor 1 antibody
      • MGC79402 antibody
      • Pitrakinra antibody
      see all

    References

    ab25114 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab25114.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up