Anti-IL6 antibody [AS16] (Biotin) (ab16164)


  • Product nameAnti-IL6 antibody [AS16] (Biotin)
    See all IL6 primary antibodies
  • Description
    Mouse monoclonal [AS16] to IL6 (Biotin)
  • ConjugationBiotin
  • SpecificityDoes not recognise panel of other human cytokines
  • Tested applicationsSuitable for: ELISAmore details
  • Species reactivity
    Reacts with: Human
    Does not react with: Mouse
  • Immunogen

    Unfortunately, this information is considered to be commercially sensitive



Our Abpromise guarantee covers the use of ab16164 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notesELISA: This antibody has been used as a solution-phase antibody at 2 µg/ml in a two-site ELISA with unconjugated IL6 antibody. Typicallly, the ELISA has a working range of 0-10000 pg/ml and sensitivity 5 pg/ml with the appropriate standard.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionCytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance.
    • Involvement in diseaseGenetic variations in IL6 are associated with susceptibility to rheumatoid arthritis systemic juvenile (RASJ) [MIM:604302]. An inflammatory articular disorder with systemic-onset beginning before the age of 16. It represents a subgroup of juvenile arthritis associated with severe extraarticular features and occasionally fatal complications. During active phases of the disorder, patients display a typical daily spiking fever, an evanescent macular rash, lymphadenopathy, hepatosplenomegaly, serositis, myalgia and arthritis.
      Note=A IL6 promoter polymorphism is associated with a lifetime risk of development of Kaposi sarcoma in HIV-infected men.
    • Sequence similaritiesBelongs to the IL-6 superfamily.
    • Post-translational
      N- and O-glycosylated.
    • Cellular localizationSecreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • Interleukin BSF 2 antibody
      • B cell differentiation factor antibody
      • B cell stimulatory factor 2 antibody
      • B-cell stimulatory factor 2 antibody
      • BSF 2 antibody
      • BSF-2 antibody
      • BSF2 antibody
      • CDF antibody
      • CTL differentiation factor antibody
      • Hepatocyte stimulatory factor antibody
      • HGF antibody
      • HSF antibody
      • Hybridoma growth factor antibody
      • Hybridoma growth factor Interferon beta-2 antibody
      • IFN-beta-2 antibody
      • IFNB2 antibody
      • IL 6 antibody
      • IL-6 antibody
      • IL6 antibody
      • IL6_HUMAN antibody
      • Interferon beta 2 antibody
      • Interferon beta-2 antibody
      • Interleukin 6 antibody
      • Interleukin 6 (interferon beta 2) antibody
      • Interleukin BSF 2 antibody
      • Interleukin-6 antibody
      see all

    References for Anti-IL6 antibody [AS16] (Biotin) (ab16164)

    ab16164 has not yet been referenced specifically in any publications.

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    Thank you for your enquiry.

    I am happy to report that these two clones, AS12 and AS16, have been validated as a suitable sandwich ELISA pair, so they should also be suitable for your streptavidin bead-based assay.

    Please let me kn...

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